Results 341 to 350 of about 2,250,672 (421)

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, EarlyView.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Erythrocyte membrane protein 3 (EMAP3) is exposed on the surface of thePlasmodium bergheiinfected red blood cell

Hernandez S, Rashpa R, Jonsdottir TK, Paoletta MS, Diaz MR, Chevalley-Maurel S, Ishizaki T, Janse CJ, Franke-Fayard B, Brochet M, Bushell ES.   +10 more
europepmc   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Harnessing Organometallic Gold(III) Complexes as Precision Scaffolds for Next‐Generation Therapeutic and Imaging Agents

ChemBioChem, Accepted Article.
Gold(III) organometallic complexes, particularly cyclometalated Au(III) compounds, have emerged as powerful tools in catalysis and bioinorganic chemistry, offering unique reactivity distinct from their Au(I) counterparts. Among their most interesting transformations, C–S cross‐coupling reactions have become a selective strategy for cysteine arylation ...
Sophie R Thomas, Riccardo Bonsignore
wiley   +1 more source

Mitochondria‐Catalyzed Activation of Anticancer Prodrugs

ChemCatChem, EarlyView.
Prodrug C is a water soluble, monomeric compound accumulating in mitochondria of cancer cells, where it is activated in the reaction with mitochondrial H2O2. The activation leads to the release of camptothecin that causes cell cycle arrest in G2 phase and cancer cell death.
Michael Raucheisen, Dina Attia, Marlies Körber, Alejandra Aroca Crevillén, Andrés Hidalgo, Frank Beierlein, Petra Imhof, Andriy Mokhir   +7 more
wiley   +1 more source

Dextran‐Assisted Biomimetic Fabrication of CdSe:Eu QDs With Enhanced Biocompatibility and Stability

Chemistry – A European Journal, EarlyView.
Dextran‐templated CdSe:Eu quantum dots were synthesized and coated with citrate or APTES to enhance stability and reduce cytotoxicity. Structural, optical, and biological evaluations demonstrated their potential for cellular imaging and theragnostic applications. Abstract A dextran templated biomimetic synthetic approach was applied for the preparation
Myrto Margariti, Marianna Roussaki, Elias Sakellis, Nikos Boukos, Maria Theodosiou, Nikoleta Kostopoulou, Eleni K. Efthimiadou   +6 more
wiley   +1 more source

SEC‐SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded‐Over Conformations

Cytoskeleton, EarlyView.
ABSTRACT Cdt1 is a mixed folded protein critical for DNA replication licensing and it also has a “moonlighting” role at the kinetochore via direct binding to microtubules and the Ndc80 complex. However, it is unknown how the structure and conformations of Cdt1 could allow it to participate in these multiple, unique sets of protein complexes.
Kyle P. Smith, Srinivas Chakravarthy, Amit Rahi, Manas Chakraborty, Kristen M. Vosberg, Marco Tonelli, Maximilian G. Plach, Arabela A. Grigorescu, Joseph E. Curtis, Dileep Varma   +9 more
wiley   +1 more source

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

Erythrocyte–Platelet Hybrid Membrane Coating for Enhanced Nanoparticle Functionalization

Advanced Materials, 2017
Ronnie H Fang, Pavimol Angsantikul, Yue Zhang   +2 more
exaly   +2 more sources