Results 81 to 90 of about 106,695 (313)

Dual Acidic pH‐Responsive Post‐Crosslinked E‐Spun Nanofibrous Scaffolds Exhibiting Enhanced Disassembly and Release for Localized Cancer Treatment

open access: yesAdvanced Healthcare Materials, EarlyView.
Dual acidic pH‐responsive degradable e‐spun nanofibrous mats crosslinked with acid‐labile imine and boronic ester linkages that exhibit rapid degradation and enhanced release of encapsulated anticancer drugs through their acid‐catalyzed hydrolysis and their doxorubicin‐loaded mats having desired antitumoral activity and hemocompatibility, as promising ...
Sofia Nieves Casillas‐Popova   +4 more
wiley   +1 more source

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou   +9 more
wiley   +1 more source

Erythrocyte Membrane Failure by Electromechanical Stress

open access: yesApplied Sciences, 2018
We envision that electrodeformation of biological cells through dielectrophoresis as a new technique to elucidate the mechanistic details underlying membrane failure by electrical and mechanical stresses.
E Du, Yuhao Qiang, Jia Liu
doaj   +1 more source

A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern

open access: yes, 2003
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Christodoulou, Z   +14 more
core   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

open access: yesAdvanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen   +19 more
wiley   +1 more source

Plasmodium falciparum erythrocyte membrane protein 1

open access: yesWikiJournal of Medicine, 2017
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a family of proteins present on the membrane surface of red blood cells (RBCs or erythrocytes) that are infected by the malarial parasite Plasmodium falciparum. PfEMP1 is synthesized during
Kholhring Lalchhandama
doaj   +1 more source

Erythrocyte-mimicking paclitaxel nanoparticles for improving biodistributions of hydrophobic drugs to enhance antitumor efficacy

open access: yes, 2020
Recent decades have witnessed several nanocrystal-based hydrophobic drug formulations because of their excellent performance in improving drug loading and controlling drug release as mediate drug forms in tablets or capsules.
Jun Yao (9646)   +6 more
core   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

open access: yesAdvanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang   +10 more
wiley   +1 more source

Erythrocyte membrane skeleton inhibits nanoparticle endocytosis

open access: yesAIP Advances, 2017
Red blood cells (RBCs), also called erythrocytes, have been experimentally proposed in recent decades as the biological drug delivery systems through entrapping certain drugs by endocytosis.
Xinli Gao   +4 more
doaj   +1 more source

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites. [PDF]

open access: yes, 2011
BACKGROUND: Malaria transmission may be considered to be homogenous with well-mixed parasite populations (as in the classic Ross/Macdonald models).
Cham, G   +59 more
core   +1 more source

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