Results 31 to 40 of about 2,963 (223)

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure

, 2012
Contains fulltext : 107961.pdf (Publisher’s version ) (Open Access)Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Dinkla, S., Brock, R.E., Dinkla, S, Cluitmans, JC, Fuchs, B, Joosten, I, Fransen, J., Tomelleri, C, Verdurmen, W.P.R., Bosman, G.J.C.G.M., Wessels, K, Schiller, J., Wessels, K., Brock, R, Fuchs, B., Verdurmen, WP, Joosten, I., Bosman, GJ, Cluitmans, J.C.A., Schiller, J, Tomelleri, C., Fransen, J   +21 more
core   +1 more source

ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Red Blood Cell Fragility and Reticulocyte Count in Hemolytic Anemic Patients with and Without G-6PD Enzyme Deficiency

Bangabandhu Sheikh Mujib Medical University Journal, 2010
Background: Erythrocyte G-6PD enzyme deficiency is an important cause of Hemolytic anemia with consequent increase in reticulocyte count. Objective: To assess the osmotic fragility of RBC status and reticulocyte count in G-6PD enzyme deficient patients ...
Monira Razzak, Noorzahan Begum, Delware Hossian   +2 more
doaj   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Modulatory Role of Antioxidant Vitamins C and E on Erythrocyte Osmotic Fragility Induced By Chronic Sodium Nitrate Administration in Rats

, 2011
Vitamin C and E supplements were administered to sodium nitrate-treated rats in order to examine the possible ameliorative effects of these antioxidants on erythrocyte osmotic fragility.
Ayo, JO, JO Ayo, IU Yarube, Yarube, IU
core   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Haematology and Erythrocyte Osmotic Fragility Indices in Domestic Chicken Following Exposure to a Polyvalent Iodophorous Disinfectant [PDF]

, 2020
The effect of prolonged use of Iodosteryl, a polyvalent iodophorous compound, as water disinfectant, on the hematology and erythrocyte osmotic fragility of the domestic chicken was investigated. Twenty eight adult male domestic chickens of the Nera black
Ademola A Oyagbemi, Oluwafikemi T Iji, Odunayo I Azeez   +2 more
core  

LACK OF RELATION BETWEEN SERUM PARATHYROID HORMONE LEVELS AND ERYTHROCYTE OSMOTIC FRAGILITY IN PEDIATRIC PATIENTS ON PERITONEAL DIALYSIS

Eurasian Journal of Medicine, 2019
Parathyroid hormone (PTH) has been shown to enhance erythrocyte osmotic fragility and has been incriminated as a factor in the anemia seen in patients with chronic renal failure and secondary hyperparathyroidism.
Celalettin Koşan, Lale Sever
doaj  

In vivo ameliorative effects of methanol leaf extract of Lawsonia inermis Linn on experimental Trypanosoma congolense infection in Wistar rats

International Journal of Veterinary Science and Medicine, 2016
The aim of this study was to investigate the ameliorative effect of Lawsonia inermis Linn used traditionally against trypanosomosis. Twenty-five adult Wistar rats of both sex were individually infected intraperitoneally (IP) with 106 Trypanosoma ...
Abdullah Mohammad Tauheed, Salisu Hashim Shittu, Mohammed Musa Suleiman, Buhari Habibu, Mohammed Umar Kawu, Patricia Ishaku Kobo, Peter Ofemile Yusuf   +6 more
doaj   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source