Results 101 to 110 of about 42,293 (332)

Erythrocytes from GGTA1/CMAH knockout pigs: implications for xenotransfusion and testing in non-human primates [PDF]

open access: yes, 2014
Background Pig erythrocytes are potentially useful to solve the worldwide shortage of human blood for transfusion. Domestic pig erythrocytes, however, express antigens that are bound by human preformed antibodies.
Burlak, Christopher   +6 more
core   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre   +5 more
wiley   +1 more source

Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]

open access: yes, 2003
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa   +3 more
core   +1 more source

Tranexamic acid therapy in pediatric cardiac surgery:a single center study [PDF]

open access: yes, 2012
Background: We conducted a retrospective study of cyanotic and acyanotic patients undergoing cardiopulmonary bypass to determine the effect of tranexamic acid on blood loss and blood products administered during the operation in pediatric cardiac surgery.
Cioffi S   +8 more
core   +1 more source

Bionic nanobombs target nasopharyngeal carcinoma to enhance the efficacy of chemoradiotherapy by destroying DNA damage repair systems

open access: yesVIEW, EarlyView.
A bionic nanomedicine system with core–shell structure (Nm‐pAu/CP/KU) was constructed. PEGylated gold nanoparticles (pAu) were loaded with cisplatin (CP) and a radiochemotherapy sensitizer (KU‐60019) to form the core pAu/CP/KU, and homologous nasopharyngeal carcinoma cell membrane vesicles (Nm) were used as the shell.
Junhua Zhang   +4 more
wiley   +1 more source

Prediction model of platelet transfusion refractoriness in patients with hematological disorders

open access: yesZhongguo shuxue zazhi
Objective To explore the risk factors for platelet transfusion refractoriness(PTR)in patients with hematological disorders, construct a prediction model and validate the model efficacy.
Shuhan YUE   +7 more
doaj   +1 more source

The effect of experimental hyperoxia on erythrocytes’ oxygen-transport function [PDF]

open access: yes, 2018
The aim of this study was to investigate the effect of hyperoxia, calcium ions and pH value on the composition of major phospholipids in human erythrocyte membranes and erythrocytes’ oxygen-transport function. To create a model of hyperoxia, we saturated
Alexander Alexandrovich Moskovkin   +25 more
core   +4 more sources

Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley   +1 more source

Evaluation of the New Lateral Flow Card MDmulticard® Basic Extended Phenotype in Routine Clinical Practice [PDF]

open access: yes, 2018
Background: Transfusion emergencies and critical situations require specifically designed devices to simplify and optimize the standard procedures. In addition, matching antigens over and above ABO-Rh-K would be beneficial. Methods: Routine blood samples
Candela-García, María-José   +5 more
core   +1 more source

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