Results 51 to 60 of about 78,012 (285)

Comorbidities in aging patients with sickle cell disease. [PDF]

open access: yes, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

Decreased erythrocyte membrane fluidity and altered lipid composition in human liver disease.

open access: yesJournal of Lipid Research, 1982
Abnormal plasma lipoproteins in patients with liver disease are associated with characteristic changes in erythrocyte membrane lipid composition. The membranes are enriched in cholesterol and phosphatidylcholine and both the cholesterol/phospholipid and ...
J S Owen   +3 more
doaj   +1 more source

Sublytic Terminal Complement Components Induce Eryptosis in Autoimmune Haemolytic Anaemia Related to IgM Autoantibodies [PDF]

open access: yes, 2019
BACKGROUND/AIMS: Eryptosis, the suicidal death of red blood cells (RBCs), is characterized by phosphatidylserine (PS) exposure at the cell surface. It can be catalysed by a variety of abnormal conditions and diseases.
Balola, Abdelwahab Hassan Ahmed   +3 more
core   +1 more source

Adipokines and Associations With Incident Osteoporotic Fracture in Patients With Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, and fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker   +9 more
wiley   +1 more source

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.

open access: yesPLoS ONE, 2007
A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced ...
Federica Verra   +14 more
doaj   +1 more source

Relationship between Red Blood cell Distribution Width and Extent of Coronary Artery Disease in Patient with ST Elevation Myocardial Infarction

open access: yesSVU - International Journal of Medical Sciences, 2021
Background: Coronary Artery Disease (CAD) is the leading cause of morbidity and mortality all around the world. Red cell distribution width (RDW) is an indicator for the variability and size of circulating erythrocytes, has recently been shown to be an ...
Mai Ahmed Hamza   +3 more
doaj   +1 more source

Basement membrane-rich Organoids with functional human blood vessels are permissive niches for human breast cancer metastasis [PDF]

open access: yes, 2013
Metastasic breast cancer is the leading cause of death by malignancy in women worldwide. Tumor metastasis is a multistep process encompassing local invasion of cancer cells at primary tumor site, intravasation into the blood vessel, survival in systemic ...
Alonso-Camino, Vanesa   +12 more
core   +4 more sources

Metabolic Abnormalities of Erythrocytes in Severe Iron Deficiency [PDF]

open access: yesBlood, 1971
Abstract Severe iron deficiency was induced in rabbits by repeated phlebotomy and maintenance on an iron-deficient diet. Erythrocytes from these animals were studied at periods of 2-10 wk following the cessation of bloodletting and were found to have a shortened survival in vivo by the 51Cr technique.
R T, Card, L R, Weintraub
openaire   +2 more sources

Effectiveness and Safety of Baricitinib for Juvenile Idiopathic Arthritis–Associated Uveitis or Chronic Anterior Antinuclear Antibody–Positive Uveitis

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan   +7 more
wiley   +1 more source

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