Results 81 to 90 of about 75,555 (208)

Structured Illumination-Based Super-Resolution Optical Microscopy for Hemato- and Cyto-Pathology Applications

Analytical Cellular Pathology, 2013
Structured illumination fluorescence microscopy utilizes interfering light and the moiré effect to enhance spatial resolution to about a half of that of conventional light microscopy, i.e. approximately 90 nm.
Tieqiao Zhang, Samantha Osborn, Chloe Brandow, Denis Dwyre, Ralph Green, Stephen Lane, Sebastian Wachsmann-Hogiu   +6 more
doaj   +1 more source

Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia

Frontiers in Physiology
Introduction: High-altitude polycythemia (HAPC) is a common chronic high-altitude disease characterized by significantly increased erythrocyte, hemoglobin (Hb), and hematocrit values and decreased arterial oxygen saturation.
Song Yu, Song Yu, Yi Ye, Tana Wuren, Hai Yi, Hai Yi   +5 more
doaj   +1 more source

Impact of Abnormal Leukocyte Count in the Pathophysiology of Sickle Cell Anemia

Journal of Blood Medicine, 2022
Tagwa Yousif Elsayed Yousif Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Gizan, 45142, Saudi ArabiaCorrespondence: Tagwa Yousif Elsayed Yousif, Department of Medical Laboratory Technology, Faculty of
Yousif TYE
doaj  

The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]

, 2020
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core   +1 more source

Stain-free artificial intelligence-assisted light microscopy for the identification of blood cells in microfluidic flow

Frontiers in Bioinformatics
The identification and classification of blood cells are essential for diagnosing and managing various haematological conditions. Haematology analysers typically perform full blood counts but often require follow-up tests such as blood smears ...
Alexander Hunt, Holger Schulze, Kay Samuel, Robert B. Fisher, Till T. Bachmann   +4 more
doaj   +1 more source

Biogenesis of the Avian Erythroid Membrane Skeleton : Receptor-mediated Assembly and Stabilization of Ankyrin (Goblin) and Spectrin [PDF]

, 1984
Ankyrin is an extrinsic membrane protein in human erythrocytes that links the αß-spectrin-based extrinsic membrane skeleton to the membrane by binding simultaneously to the ß-spectrin subunit and to the transmembrane anion transporter.
Lazarides, Elias, Moon, Randall T.
core  

Intercellular adhesion molecule-4 and CD36 are implicated in the abnormal adhesiveness of sickle cell SAD mouse erythrocytes to endothelium

Haematologica, 2010
Background Abnormal adhesiveness of red blood cells to endothelium has been implicated in vaso-occlusive crisis of sickle cell disease. The present study examined whether the SAD mouse model exhibits the same abnormalities of red blood cell adhesion as ...
Marie-Marcelle Trinh-Trang-Tan, Camilo Vilela-Lamego, Julien Picot, Marie-Paule Wautier, Jean-Pierre Cartron   +4 more
doaj   +1 more source

A secretory protein neudesin regulates splenic red pulp macrophages in erythrophagocytosis and iron recycling

Communications Biology
Neudesin, originally identified as a neurotrophic factor, has primarily been studied for its neural functions despite its widespread expression. Using 8-week-old neudesin knockout mice, we elucidated the role of neudesin in the spleen.
Yoshiaki Nakayama, Yuki Masuda, Takehiro Mukae, Tadahisa Mikami, Ryohei Shimizu, Naoto Kondo, Hiroshi Kitagawa, Nobuyuki Itoh, Morichika Konishi   +8 more
doaj   +1 more source

Integrating Deep Learning into Genotoxicity Biomarker Detection for Avian Erythrocytes: A Case Study in a Hemispheric Seabird

Mathematical and Computational Applications
Recently, nuclear abnormalities in avian erythrocytes have been used as biomarkers of genotoxicity in several species. Anomalous shapes are usually detected in the nuclei by means of microscopy inspection.
Martín G. Frixione, Facundo Roffet, Miguel A. Adami, Marcelo Bertellotti, Verónica L. D’Amico, Claudio Delrieux, Débora Pollicelli   +6 more
doaj   +1 more source

OSMOMETRIC BEHAVIOR OF NORMAL AND ABNORMAL HUMAN ERYTHROCYTES [PDF]

Blood, 1948
Abstract Normal human erythrocytes suspended in the series of hypotonic salt solutions employed for testing red cell fragility behave like nearly perfect osmometers throughout the series, with their maximum swelling, usually around 175 per cent of their initial volume, sharply defined by their mean surface area.
openaire   +2 more sources