Results 111 to 120 of about 680,017 (354)

Dielectric behavior of oblate spheroidal particles: Application to erythrocytes suspensions

, 2002
We have investigated the effect of particle shape on the eletrorotation (ER) spectrum of living cells suspensions. In particular, we consider coated oblate spheroidal particles and present a theoretical study of ER based on the spectral representation ...
Huang, J. P., Yu, K. W.
core   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Statistical classification of erythrocytes in hereditary spherocytosis based on the spectral features of cell surfaces’ AFM images

Informatika, 2019
The method of classification of erythrocytes (red blood cells) based on spectral features of the cell surface images (of physical-mechanical properties maps) obtained with an atomic-force microscope (AFM) is proposed.
I. E. Starodubtsev, Yu. S. Kharin, M. S. Abramovich   +2 more
doaj  

Biochemical and hematological blood parameters in dogs with epilepsy differentiated by the level of neuroinfectious antigenic pressure

Theoretical and Applied Veterinary Medicine
In recent decades, researchers have established that the altered status of trace elements plays an important role in epilepsy in both humans and dogs.
O. O. Portuheis
doaj   +1 more source

Fast detection and quantification of Plasmodium species infected erythrocytes in a non-endemic region by using the Sysmex XN-31 analyzer [PDF]

, 2022
Tania A. Khartabil, Yolanda B. de Rijke, Rob Koelewijn, Jaap J. van Hellemond, Henk Russcher   +4 more
openalex   +1 more source

Diffusion-limited Reaction of Free Nitric Oxide with Erythrocytes*

Journal of Biological Chemistry, 1998
Concentration changes of nitric oxide (NO) were monitored using an NO-sensitive electrode in phosphate-buffered saline (PBS) with either free oxyhemoglobin (oxyHb) or red blood cells (RBCs).
Xiaoping Liu, Mark J. S. Miller, M. Joshi, H. Sadowska-Krowicka, D. Clark, J. Lancaster   +5 more
semanticscholar   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

Advanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son, Kyusoon Pak, Taehoon Lee, Monica Celine Prayogo, Jinyoung Choi, Sukkyung Kang, Minjoo Kang, Byungkook Oh, Sang Yu Sun, Sanha Kim, Sung Gap Im, Sangyong Jon, Steve Park   +12 more
wiley   +1 more source

Red blood cells in cerebrospinal fluid as possible inhibitory factor for enterovirus RT-PCR

Arquivos de Neuro-Psiquiatria
The presence of hemoglobin in samples are considered an important inhibitory factor for polymerase chain reaction (PCR). The aim of this study was to examine the influence of red blood cells (RBC)s in cerebrospinal fluid (CSF) as an inhibitory factor to ...
Sérgio Monteiro de Almeida, Sônia Mara Raboni, Meri Bordignon Nogueira, Luine R. Renaud Vidal   +3 more
doaj   +1 more source