Results 241 to 250 of about 495,043 (357)

Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease. [PDF]

open access: yesProc Natl Acad Sci U S A
Romero LO   +9 more
europepmc   +1 more source

The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment.

open access: yesBlood, 2012
A. Risitano   +11 more
semanticscholar   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

Electron Microscopy of Erythrocytes from Chickens Affected with Chronic Respiratory Disease

open access: hybrid, 1955
Reginald L. Reagan   +4 more
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

open access: yesAdvanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang   +13 more
wiley   +1 more source

Urinary carbonic anhydrase 1 as a marker of hematuria in IgA nephropathy. [PDF]

open access: yesNephrol Dial Transplant
Post TGJM   +6 more
europepmc   +1 more source

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui   +18 more
wiley   +1 more source

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