Results 271 to 280 of about 495,043 (357)

Brain-cervical lymph node crosstalk contributes to brain injury induced by subarachnoid hemorrhage in mice. [PDF]

Nat Commun
Chen J, Wang J, Zheng W, Ding W, Zhuang Z, Xu H, Ding W, Xu T, Wang L, Li N, Zhao Y, Shi Q, Xing L, Wang Y, Liang Q.   +14 more
europepmc   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

A CD47 antibody with minimized erythrocyte and thrombocyte toxicities. [PDF]

Front Oncol
Pei M, Dai XD, Jiang XF, Yuan CY, Tan J, He KF, Liu GJ, Zhu JD, Li HH, Pan AL, Wang YR, Chen YL, Chen XJ, Wang C.   +13 more
europepmc   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Blood group antigens and malaria susceptibility. [PDF]

Front Cell Infect Microbiol
Liu FF, Liang J, Gao M, Li K.
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Bacterial adhesion and erythrocyte integrity on polycaprolactone nanowire surfaces. [PDF]

RSC Adv
Sathyanarayanan V, Madruga LYC, Pereira BL, Soares P, Popat KC.   +4 more
europepmc   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Ultrasensitive ELISA for Accurate Detection of <i>Plasmodium falciparum</i> Infection. [PDF]

Open Forum Infect Dis
Kobayashi Y, Okita K, Chen PK, Hasunuma M, Tsuneki T, Hayakawa ESH, Yoshimura T, Ito E.   +7 more
europepmc   +1 more source

The assay of staphylococal delta-haemolysin with fish erythrocytes [PDF]

, 1976
L. P. Chao
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