Results 291 to 300 of about 448,913 (359)

ACSS2/AATF Drives Soluble FasL‐Mediated CD8+ T Cell Apoptosis in Pancreatic Neuroendocrine Tumors

open access: yesAdvanced Science, EarlyView.
This study unveils that ACSS2‐driven acetate metabolism fuels histone pan‐acetylation in pancreatic neuroendocrine tumors (PNETs), remodeling the epigenetic landscape. The ACSS2/AATF axis transcriptionally activates soluble FasL (sFasL), which engages Fas receptors on infiltrating CD8+ T cells to trigger caspase‐8/3‐mediated apoptosis.
Qin Dang   +14 more
wiley   +1 more source

Molecular diagnosis of hemoplasma infection in cats and sheep with hematological studies. [PDF]

open access: yesOpen Vet J
Ouda SE   +7 more
europepmc   +1 more source

Spatial Transcriptomics Reveals Transcriptomic and Immune Microenvironment Reprogramming during Thyroid Carcinoma Dedifferentiation

open access: yesAdvanced Science, EarlyView.
Spatial transcriptomic analysis of Anaplastic thyroid carcinoma (ATC)‐differentiated thyroid carcinoma (DTC) coexisting tumors reveals that coexisting DTC regions with ATC‐like genomic alterations undergo sequential transcriptomic reprogramming and immune microenvironment remodeling, ultimately evolving into a full ATC pathological phenotype.
Kang Ning   +19 more
wiley   +1 more source

Metabolic alterations in erythrocytes associated with long-term hypoxia at high altitude. [PDF]

open access: yesBMC Genomics
Yu T   +13 more
europepmc   +1 more source

Enhanced Visualization of Erythrocytes Through Photoluminescence Using NaYbF<sub>4</sub>:Yb<sup>3+</sup>,Er<sup>3+</sup> Nanoparticles. [PDF]

open access: yesBiosensors (Basel)
Torres-Vera V   +8 more
europepmc   +1 more source

A semi-mechanistic population pharmacokinetic-pharmacodynamic model to assess downstream drug-target effects on erythropoiesis. [PDF]

open access: yesJ Pharmacokinet Pharmacodyn
Rognås SV   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy