Results 81 to 90 of about 7,240 (211)

Immunophenotypic characteristics of plasma cells in POEMS syndrome

Cytometry Part B: Clinical Cytometry, Volume 110, Issue 4, Page 266-273, July 2026.
Abstract To analyze the immunophenotypic characteristics of plasma cells in patients with polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes (POEMS) syndrome. This retrospective study included patients with POEMS syndrome hospitalized in the Department of Hematology, Huashan Hospital, from September 2017 to August 2025 ...
Zhenhua Wang, Tianling Ding, Beiqian Wu, Qiang Niu, Leyao Gu, Yan Yuan, Ping Zhu   +6 more
wiley   +1 more source

Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models

Haematologica, 2018
Activated erythropoietin (EPO) receptor (EPOR) signaling causes erythrocytosis. The important role of macrophages for the erythroid expansion and differentiation process has been reported, both in baseline and stress erythropoiesis.
Jieyu Wang, Yoshihiro Hayashi, Asumi Yokota, Zefeng Xu, Yue Zhang, Rui Huang, Xiaomei Yan, Hongyun Liu, Liping Ma, Mohammad Azam, James P. Bridges, Jose A. Cancelas, Theodosia A. Kalfa, Xiuli An, Zhijian Xiao, Gang Huang   +15 more
doaj   +1 more source

Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal, and muscular degeneration [PDF]

, 2006
To investigate the consequences of inborn excessive erythrocytosis, we made use of our transgenic mouse line (tg6) that constitutively overexpresses erythropoietin (Epo) in a hypoxia-independent manner, thereby reaching hematocrit levels of up to 0.89 ...
Heinicke, Katja, Djonov, Valentin, Wagner, Peter D, Stallmach, Thomas, Weber, Klaus, Vogel, Johannes, Gassmann, Max, Baum, Oliver, Ogunshola, Omolara O, Keller, Stephan, Wolfer, David P   +10 more
core   +1 more source

Autoimmunity and peginterferon therapy for polycythemia vera

HemaSphere, Volume 10, Issue 7, July 2026.
Abstract Peginterferon‑α is useful to treat myeloproliferative neoplasms (MPNs) but can precipitate broad autoimmunity. By promoting beta‐cell, thyroid, and systemic immune injury, it can lead to Type 1 diabetes, autoimmune thyroiditis, systemic lupus erythematosus, or Sjögren's syndrome.
Etienne Rivière, Alexandre Guy, Olivier Mansier, Clémence Mediavilla, Jean‐Jacques Kiladjian, Chloé James, Patrick Blanco, Estibaliz Lazaro, Jean‐François Viallard   +8 more
wiley   +1 more source

First Report of Co‐Inheritance of Hemoglobin British Columbia (HBB:c.304G>A) and β‐Thalassemia IVS‐I‐6 (HBB:c.92+6T>C): Clinical Characterization of an Iranian Case

Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.
ABSTRACT Background Hemoglobin British Columbia is a rare high‐oxygen‐affinity β‐globin variant caused by the HBB:c.304G>A substitution. Its detection is exceptionally uncommon, particularly in the Middle East, and may lead to diagnostic pitfalls when relying solely on hemoglobin separation techniques.
Kimia Fathalizade, Mahsa Kiani Bigdeli, Seyed Sajad Eghbali, Mohammadtaghi Ghiyasi, Roz Rastgoo, Mohammad Javad Mousavi   +5 more
wiley   +1 more source

Erythrocytosis after liver transplantation: The experience of a university hospital [PDF]

, 2013
he prevalence and causes of erythrocytosis after liver transplantation have never been studied, even though this condition is known to predispose patients to thrombosis leading to graft failure or death.
Gabriella Cordone, Lucienne Pellegrini, Gianpaolo Parrilli, CIACCI, Carolina, Vincenzo Martinelli, Carolina Ciacci, Giuseppe Cardillo, Novella Pugliese, ZINGONE, FABIANA   +8 more
core   +1 more source

Reference Interval Establishment for Four Coagulation Parameters Using Indirect Methods in a High‐Altitude Chinese Population: A Retrospective Real‐World Analysis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.
This study established reference intervals for APTT, PT, TT, and FIB in a Tibetan high‐altitude population using two indirect algorithms, Hoffmann and refineR. The established RIs differed significantly from those of low‐altitude regions, highlighting the need for region‐specific RIs to ensure accurate evaluation of coagulation disorders.
Banjiu Zhaxi, Danni Mu, Shengfang Ye, Chaochao Ma, Zhen Da, Yichen Ma, Yumeng Gao, Shensong Li, Yixicuomu, Zhaxiyangzong, Jinrong Pang, Mingjun Zhan, Ling Qiu, Qu Dan, Xinqi Cheng, Zhijuan Liu   +15 more
wiley   +1 more source

Case Report: A rare form of congenital erythrocytosis due to SLC30A10 biallelic variants—differential diagnosis and recommendation for biochemical and genetic screening

Frontiers in Pediatrics
Congenital erythrocytosis recognizes heterogeneous genetic basis and despite the use of NGS technologies, more than 50% of cases are still classified as idiopathic.
Rosalinda Giannini, Emanuele Agolini, Giuseppe Palumbo, Giuseppe Palumbo, Antonio Novelli, Giacomo Garone, Giacomo Garone, Melissa Grasso, Giovanna Stefania Colafati, Marta Matraxia, Eleonora Piccirilli, Annalisa Deodati, Annalisa Deodati, Giulia Ceglie, Giulia Ceglie   +14 more
doaj   +1 more source

Activin Signaling Inhibitors in Pulmonary Hypertension: A State‐of‐the‐Art Review

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Pulmonary arterial hypertension (PAH) is a disease of abnormal pulmonary vascular remodeling and vascular obliteration that results in right heart failure and death. PAH pathogenesis is strongly associated with mutations of the Transforming Growth Factor Beta (TGF‐β) superfamily signaling pathway, which has previously been challenging to ...
Sudarshan Rajagopal, Joseph Abueg, Kevin M. Hart, Edmund Lau, Eliana C. Martinez, Nicholas W. Morrell, Ioana R. Preston, Sandeep Sahay, Namita Sood, Paul B. Yu, Nayeli G. Zayas‐Hernández   +10 more
wiley   +1 more source

Benign Metastasizing Leiomyoma With Myomatous Erythrocytosis Syndrome: First Reported Coexistence as a Unified Hormonal Syndrome

Respirology Case Reports, Volume 14, Issue 7, July 2026.
Time course of haemoglobin (red, left axis) and serum erythropoietin (blue, right axis) before and after hysterectomy with bilateral salpingo‐oophorectomy (BSO, green vertical line, 31 July 2025), showing normalization of both parameters following tumour resection.
Venkatkiran Kanchustambham, Ashley McWalter, Oluwatobi E. Odetola, Recep Nigdelioglu   +3 more
wiley   +1 more source