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Coronavirus (SARS-CoV-2) Deactivation via Spike Glycoprotein Shielding by Old Drugs: Molecular Docking Approach [PDF]
Journal of Epigenetics, 2021 Today the disease of COVID-19 comprises the most serious problem against human health worldwide with a high rate of virulence and mortality. The disease is caused by the SARS-CoV-2 virus from the beta coronavirus family.
Mohammad Reza Dayer
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Antibiotics, 2023 Background: Studies have demonstrated that the gut microbiome changes upon exposure to systemic antibiotics. There is a paucity of literature regarding impact on the gut microbiome by long-term usage of erythromycin ethyl succinate (EES) when utilized as
Aravind Thavamani +6 more
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Erythromycin Formulations—A Journey to Advanced Drug Delivery
Pharmaceutics, 2022 Erythromycin (ERY) is a macrolide compound with a broad antimicrobial spectrum which is currently being used to treat a large number of bacterial infections affecting the skin, respiratory tract, intestines, bones and other systems, proving great value ...
Vera-Maria Platon +2 more
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Frontiers in Microbiology, 2021 Rv3197 (MABP-1), a non-canonical ABC protein in Mycobacterium tuberculosis, has ATPase activity and confers inducible resistance to the macrolide family of antibiotics. Here we have shown that MSMEG_1954, the homolog of Rv3197 in M.
Qingqing Zhang +10 more
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Pathogens, 2023 The diversity and composition of intestinal microbiota in rainbow trout have been studied using next-generation sequencing (NGS), although few studies have examined the effects of antimicrobials.
David Huyben +4 more
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Gels, 2023 Erythromycin (EM) is a macrolide antibiotic that is frequently used to treat skin bacterial infections. It has a short half-life (1–1.5 h), instability in stomach pH, and a low oral bioavailability.
Marwa H. Abdallah +7 more
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Microbiology Spectrum, 2021 Streptococcus pneumoniae, the most common cause of community-acquired pneumonia, causes severe invasive infections, including meningitis and bacteremia. The widespread use of macrolides has been reported to increase the prevalence of macrolide-resistant ...
Hisanori Domon +8 more
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Microorganisms, 2023 Antibiotics are one of the greatest scientific achievements of modern medicine, but excessive use is creating challenges for the future of medicine.
Francesco Di Pierro +10 more
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Клинический разбор в общей медицине, 2023 Gastrointestinal dysfunction is a disorder often found in critically ill patients that leads to nutritional deficiency resulting in the increase of the number of adverse events during hospitalization, more frequent hospital readmissions and steady ...
Nikolai P. Krotenko, Marina S. Grinenko
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