Results 221 to 230 of about 94,345 (348)

MMS22L is a novel key actor of normal and pathological erythropoiesis. [PDF]

open access: yesHemasphere
Colin E   +31 more
europepmc   +1 more source

Brentuximab Vedotin With Adriamycin, Vinblastine, and Dacarbazine for Patients Aged 18–59 Years With Untreated Advanced Stage Classical Hodgkin Lymphoma: The Largest Real‐Life Series From Southern Italy Cancer Centers

open access: yesEuropean Journal of Haematology, Volume 116, Issue 2, Page 174-184, February 2026.
ABSTRACT BV + AVD is increasingly used for frontline treatment of stage III/IV cHL. Young adults and adults (Ya&A) were the most common patients treated with BV + AVD in clinical trials but have not been studied in non‐trial settings. We conducted a real‐life study in secondary and tertiary cancer centers to evaluate the PFS in 18–59 years aged ...
Marco Picardi   +28 more
wiley   +1 more source

Lymphoid Organs Remodeling in Non‐Obese Diabetic Goto‐Kakizaki Rats Immunized With SARS‐CoV‐2 Antigens

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
The Goto‐Kakizaki rat, a non‐obese model of type 2 diabetes mellitus (T2DM), exhibits lymphoid organ remodeling, including baseline thymic involution and splenic white pulp reorganization. Following completion of a three‐dose SARS CoV‐2 antigen immunization protocol, anti‐Spike IgG levels were significantly increased despite these structural changes ...
Sara Araujo Pereira   +11 more
wiley   +1 more source

Enhancer‐dependent gene regulation in space, time, and malignancies

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 357-367, 15 January 2026.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum   +2 more
wiley   +1 more source

IL-17 stimulates erythropoiesis in vivo by amplifying the response of erythroid progenitors to erythropoietin. [PDF]

open access: yesPLoS Biol
Wu QC   +7 more
europepmc   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei   +12 more
wiley   +1 more source

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