Results 21 to 30 of about 1,436 (153)

In vitro Assessment of Solar Filters for Erythropoietic Protoporphyria in the Action Spectrum of Protoporphyrin IX

Frontiers in Medicine, 2021
Introduction: Subjects with erythropoietic protoporphyria rely on broad-spectrum sunscreens with high sun protection factor, which is not informative on efficacy in the absorption spectrum of protoporphyrin IX, spanning visible radiation and peaking ...
Alvise Sernicola, Elena Cama, Maria Guglielmina Pelizzo, Maria Guglielmina Pelizzo, Enrico Tessarolo, Annamaria Nicolli, Giulia Viero, Mauro Alaibac   +7 more
doaj   +1 more source

From darkness to light: Case report on afamelanotide-treatment in a 9-year-old child with erythropoietic protoporphyria. [PDF]

JAAD Case Rep
Minder AE, Barman-Aksözen J.
europepmc   +2 more sources

Erythropoietic protoporphyria

Acta Dermato-Venereologica, 1971
No abstract ...
G, Hovding, O I, Haavelsrud, N, Wad
openaire   +4 more sources

Cimetidine for erythropoietic protoporphyria

Photodiagnosis and Photodynamic Therapy, 2022
Erythropoietic protoporphyria (EPP) is caused by deficiency of the enzyme converting protoporphyrin IX (PpIX) into heme resulting in accumulation of PpIX; leading to photosensitivity and liver toxicity. Cimetidine might inhibit δ-aminolevulinic acid synthase influencing the heme biosynthesis.
Heerfordt, Ida M., Lerche, Catharina M., Wulf, Hans Christian   +2 more
openaire   +4 more sources

The role of allogeneic stem cell transplantation in severe erythropoietic protoporphyria in adults and young adults: timing and modalities. [PDF]

Hematol Transfus Cell Ther
Frieri C, Poli A, Balsat M, de Fontbrune FS.   +3 more
europepmc   +2 more sources

Correction: Erythropoietic protoporphyria: case reports for clinical and therapeutic hints. [PDF]

Ital J Pediatr
Tumminelli C, Burlo F, Pastore S, Severini GM, Berti I, Marchini S, Zanon D, De Martino E, Tommasini A.   +8 more
europepmc   +2 more sources

The role of ClpX in erythropoietic protoporphyria

Hematology, Transfusion and Cell Therapy, 2018
Hemoglobin is an essential biological component of human physiology and its production in red blood cells relies upon proper biosynthesis of heme and globin protein.
Jared C. Whitman, Barry H. Paw, Jacky Chung   +2 more
doaj   +1 more source

Absorption, metabolism, and excretion of [14C]dersimelagon, an investigational oral selective melanocortin 1 receptor agonist, in preclinical species and healthy volunteers

Pharmacology Research & Perspectives, 2023
Dersimelagon (formerly MT‐7117) is a novel, orally administered nonpeptide small molecule selective agonist for melanocortin 1 receptor currently being investigated for the treatment of erythropoietic protoporphyria, X‐linked protoporphyria, and diffuse ...
Minoru Tsuda, Kei Ogawa, Tadashi Endou, Takahiro Goto, Yuko Ogasawara, Akihito Ogasawara   +5 more
doaj   +1 more source

Dersimelagon in Erythropoietic Protoporphyrias

New England Journal of Medicine, 2023
Erythropoietic protoporphyria and X-linked protoporphyria are inborn errors of heme biosynthesis that cause elevated circulating levels of metal-free protoporphyrin and phototoxicity. Both disorders are characterized by excruciating phototoxic attacks after exposure to visible light.
Manisha, Balwani, Herbert L, Bonkovsky, Cynthia, Levy, Karl E, Anderson, D Montgomery, Bissell, Charles, Parker, Fumihiro, Takahashi, Robert J, Desnick, Kirstine, Belongie   +8 more
openaire   +5 more sources

Erythropoietic Protoporphyria in a Japanese Population

Acta Dermato-Venereologica, 2019
Erythropoietic protoporphyria is caused by a partial deficiency of ferrochelatase, which is the last enzyme in the heme biosynthesis pathway. In a typical erythropoietic protoporphyria, photosensitivity initially appears, following the first exposure to ...
Megumi Mizawa, Teruhiko Makino, Hajime Nakano, Daisuke Sawamura, Tadamichi Shimizu   +4 more
doaj   +1 more source