Results 1 to 10 of about 17,235 (261)
Comparison of Phototoxicity Sensitivity by the Neutral Red Uptake Method for BALB/c 3T3, HaCaT, and HDFa Cells In Vitro [PDF]
Innovations in Digital Health, Diagnostics, and Biomarkers, 2022 Introduction: Phototoxicity is an acute photoinduced reaction. The 3T3 neutral red uptake (NRU) phototoxicity test has high sensitivity for the determination of phototoxic substances. To further optimize the method, this study mainly focused on comparing
Qiuwen Liang, Feifei Wang, Xiao Ma
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Exploration of alternative test methods to evaluate phototoxicity of ophthalmic agents by using Statens Seruminstitut Rabbit Cornea cell lines and 3D human reconstituted cornea models. [PDF]
PLoS ONE, 2018 Many chemicals have been reported to induce phototoxicity. The absorbance of light energy within the sunlight range is a common characteristic of phototoxicity.
Soyoung Kim, Ki Hwan Choi, Jaesuk Yun
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Cell death mechanisms in retinal phototoxicity
Journal of Photochemistry and Photobiology, 2023 Retinal phototoxicity is the main mechanism by which light induces damage to the retina, the sensitive part of the eye. The impact of light on the different retinal layers varies depending on several factors including the wavelength of the incident light,
Anaïs Françon, Alicia Torriglia
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Locally Administered Photodynamic Therapy for Cancer Using Nano-Adhesive Photosensitizer
Pharmaceutics, 2023 Photodynamic therapy (PDT) is a great potential anti-tumor therapy owing to its non-invasiveness and high spatiotemporal selectivity. However, systemically administered photosensitizers diffuse in the skin and the eyes for a long duration, which cause ...
Yoshiki Komatsu +7 more
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Laboratory Animal Research, 2020 Some drugs cause phototoxicity in humans when exposed to light, thus there is a need for an in vivo phototoxicity test to evaluate them. However, an in vivo phototoxicity test method to evaluate this has not been established.
Nam Hee Youn +7 more
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Frontiers in Cell and Developmental Biology, 2021 Phototoxicity is a significant constraint for live cell fluorescence microscopy. Excessive excitation light intensities change the homeostasis of the observed cells.
Rana A. Alghamdi +6 more
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Cells, 2022 Phototoxicity induced by antibiotics is a real problem in health care. The discontinuation of antibiotic therapy due to a phototoxic reaction can lead to the development of resistant strains.
Justyna Kowalska +5 more
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Challenges in 3D Live Cell Imaging
Photonics, 2021 A short overview on 3D live cell imaging is given. Relevant samples are described and various problems and challenges—including 3D imaging by optical sectioning, light scattering and phototoxicity—are addressed.
Herbert Schneckenburger, Verena Richter
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Bioengineering & Translational Medicine, 2023 We used a blue organic light‐emitting diode (bOLED) to increase the paracrine factors secreted from human adipose‐derived stem cells (hADSCs) for producing conditioned medium (CM).
Sung‐Won Kim +3 more
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Frontiers in Allergy, 2022 Drug-induced photosensitivity (DIP) is a common cutaneous adverse drug reaction, resulting from the interaction of ultraviolet radiations, mostly ultraviolet A, with drugs. DIP includes phototoxicity and photoallergy.
Luca Di Bartolomeo +10 more
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