Results 11 to 20 of about 6,711 (234)
, 2002 Phototoxicity occurs when a substance is toxic only under the action of light, and can, depending on the mechanism of toxic action, be divided into type I and type II phototoxicity.
Lars Olof Björn, Pirjo Huovinen
openaire +2 more sources
Inhibition of ABCG2 prevents phototoxicity in a mouse model of erythropoietic protoporphyria
Nature CommunicationsErythropoietic protoporphyria (EPP) is a genetic disease characterized by protoporphyrin IX-mediated painful phototoxicity. Currently, options for the management of EPP-associated phototoxicity are limited and no oral medication is available.
Junjie Zhu +8 more
doaj +2 more sources
Central scotoma following phacoemulsification surgery: A case report on retinal phototoxicity
American Journal of Ophthalmology Case ReportsPhacoemulsification cataract surgery is a widely adopted, however despite its routine application and favorable outcomes, it is not devoid of risks. Complications are rare, with an even more infrequent occurrence of retinal phototoxicity.
Tahmina Nazari, Maarten B. Jalink
doaj +3 more sources
EXPERIMENTAL TESTING OF AN IN VIVO METHOD OF PHOTOTOXICITY EVALUATION [PDF]
Регуляторные исследования и экспертиза лекарственных средств, 2018 At present all new medicinal products and cosmetics that absorb medium-wavelength UVB, long-wavelength UVA, or visible light in the range 290–700 nm need to be tested for potential phototoxicity.
V. А. Vavilova +5 more
doaj +2 more sources
Antioxidant inhibition of porphyrin-induced cellular phototoxicity
, 2001 Porphyrins such as protoporphyrin IX (PP IX) and uroporphyrin I (UP I) can be phototoxic to human cells. To study the protective ability of antioxidants (beta-carotene, lycopene, ascorbic acid and alpha-tocopherol), against such porphyrin phototoxicity ...
Bohm, F +4 more
core +9 more sources
Genetically Encoded Red Photosensitizers with Enhanced Phototoxicity [PDF]
, 2020 Genetically encoded photosensitizers are increasingly used as optogenetic tools to control cell fate or trigger intracellular processes. A monomeric red fluorescent protein called SuperNova has been recently developed, however, it demonstrates suboptimal
Staroverov, Dmitry B +7 more
core +1 more source
Characterization of phototoxicity reactions in human and animal skin models [PDF]
, 2013 Phototoxicity is a relatively common phenomenon and is an adverse effect of some systemic drugs. A large number of pharmaceutical drug substances are known to carry the potential to elicit a phototoxic response (Moore 2002, Ferguson 2002). Reported cases
Boudon, Stéphanie
core +1 more source
Nature Communications, 2020 Live cell imaging of mitochondrial cristae is challenged by the unsuitability of current fluorescent probes and high phototoxicity. Here the authors develop a squarine variant probe (MitoESq-635) that is capable of longitudinal imaging of cristae with ...
Xusan Yang +13 more
doaj +1 more source
Phototoxicity: Its mechanism and animal alternative test methods
, 2021 The skin exposure to solar irradiation and photoreactive xenobiotics may produce abnormal skin reaction, phototoxicity. Phototoxicity is an acute light-induced response, which occurs when photoreacive chemicals are activated by solar lights and ...
임경민
core +1 more source
Antioxidants, 2023 A Pacific brittle star Ophiura sarsii has previously been shown to produce a chlorin (3S,4S)-14-Ethyl-9-(hydroxymethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid (ETPA) (1) with potent phototoxic activities, making it applicable to ...
Antonina Klimenko +11 more
doaj +1 more source