Results 71 to 80 of about 3,099 (193)
Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 4, April 2025.Vemurafenib (VEM) induces renal tubular toxicity through mitochondrial dysfunction and lysosomal abnormalities. Superoxide production is a key factor, and mitochondrial antioxidant XJB‐5‐131 partially alleviated this toxicity. Autophagy impairment is also suggested.
Akimasa Sanagawa, Hiroshi Takase
wiley +1 more source
British Journal of Haematology, Volume 207, Issue 3, Page 1148-1151, September 2025.
Danja Schulenburg‐Brand +6 more
wiley +1 more source
The Journal of Dermatology, Volume 52, Issue 3, Page 416-422, March 2025.Abstract Erythropoietic protoporphyria (EPP) and X‐linked protoporphyria (XLP) are rare genetic disorders. There are limited data regarding how these disorders are managed in real‐world settings. The aim of this study was to document the characteristics and treatment patterns among patients diagnosed with EPP or XLP in general real‐world settings in ...
Samuel M. Silver +4 more
wiley +1 more source
Biokémiai, molekuláris biológiai és genetikai vizsgálatok napfény okozta bőrkárosodásokban = Development of environmental health education: physical, chemical, epidemiological and dermatological aspects, with special emphasis on radiation induced damage [PDF]
, 2012 Munkacsoportunk évtizedek óta foglalkozik az ultraibolya fény élettani és patofiziológiai hatásaival klinikai és molekuláris szinten. Jelen pályázat futamideje alatt több photodermatologiai témájú összefoglaló közleményt és egy monográphiát publikáltunk.
Benkő, Szilvia +10 more
core
Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]
, 2016 Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A. +3 more
core +2 more sources
Liver transplantation and primary liver cancer in porphyria
Liver International, Volume 45, Issue 3, March 2025.Abstract The porphyrias are a heterogeneous group of metabolic disorders that result from defects in heme synthesis. The metabolic defects are present in all cells, but symptoms are mainly cutaneous or related to neuropathy. The porphyrias are highly relevant to hepatologists since patients can present with symptoms and complications that require liver
Mattias Lissing +2 more
wiley +1 more source
Erythropoietic Protoporphyria Masquerading as Angioedema in a 4-Year-Old Female
Allergy, Asthma & Clinical Immunology, 2006 Angioedema is a common presentation with a broad differential, including rare disorders with which an allergist must be familiar. Our objective was to report a case of swelling of the hands and feet mimicking angioedema with hepatomegaly in a 4-year-old ...
Wang Helen C, Yousef Ejaz
doaj +1 more source
Practical recommendations for biochemical and genetic diagnosis of the porphyrias
Liver International, Volume 45, Issue 3, March 2025.Abstract The porphyrias are a group of rare inborn errors of metabolism associated with various clinical presentations and long‐term complications, making them relevant differential diagnoses to consider for many clinical specialities, especially hepatologists, gastroenterologists and dermatologists.
Aasne K. Aarsand +4 more
wiley +1 more source
Photosensitivity Skin Disorders in Childhood [PDF]
, 2010 Photosensitivity in childhood is caused by a diverse group of diseases. A specific sensitivity of a child’s skin to ultraviolet light is often the first manifestation or a clinical symptom of photodermatosis.
Ines Sjerobabski-Masnec +4 more
core +1 more source
RareErythropoietic protoporphyria (EPP) is a rare genetic disorder that can lead to liver complications in a subset of patients. We describe the case of a 36-year-old woman with genetically confirmed EPP who developed acute liver injury following the second ...
Francesca Granata +4 more
doaj +1 more source