Results 41 to 50 of about 16,252 (181)
Hyporesponsiveness to recombinant human erythropoietin [PDF]
Nephrology Dialysis Transplantation, 2001 The introduction of recombinant human erythropoietin (rh-Epo, epoetin) as a treatment for the anaemia of renal failure has transformed the management of this condition. Nevertheless, a significant number of patients fail to respond. There are many different possible causes of inadequate response to epoetin.
openaire +2 more sources
Therapeutic Apheresis and Dialysis, Volume 30, Issue 4, Page 585-593, August 2026.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Neuroprotective mechanisms of erythropoietin in a rat stroke model
Translational Neuroscience, 2020 This study was designed to investigate the indirect neuroprotective properties of recombinant human erythropoietin (rhEPO) pretreatment in a rat model of transient middle cerebral artery occlusion (MCAO).
Juenemann Martin +11 more
doaj +1 more source
Folia Medica Indonesiana, 2021 Anemia in patient with chronic kidney disease could cause a lot of complication. The first line therapy of this condition is by treating with erythropoiesis-stimulating agents (ESA) or called erythropoietin.
Anak Agung Ngurah Putra Riana Prasetya +2 more
doaj +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, Volume 16, Issue 8, Page 1509-1526, August 2026.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Correction of ischemic optic neuropathy in rats by carbamylated darbepoetin [PDF]
Research Results in Pharmacology, 2018 Introduction: The protective effects of carbamylated darbepoetin on the model of ischemic optic neuropathy in rats were revealed. Objectives: To increase the effectiveness of pharmacological correction of experimental ischemic optic neuropathy in
Anna A. Peresypkina
doaj +3 more sources
A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders
Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 357-374, August 2026.Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel +3 more
wiley +1 more source
NEUROPROTECTIVE EFFECTS OF ERYTHROPOIETIN: OPPORTUNITIES, PROSPECTS AND REALITY (REVIEW)
Медицинский вестник Юга России, 2014 The review presents an analysis of experimental and clinical studies on the neuroprotective properties of erythropoietin. The suggestion about possible participation of deficiency of erythropoietin in the development of cerebral disorders in patients ...
I. Kladova +7 more
doaj +1 more source
PHARMACOLOGICAL PRECONDITIONING BY RECOMBINANT ERYTHROPOIETIN AS THE POSSIBILITY OF INCREASING THE STABILITY OF TISSUE OF THE RETINA TO REPERFUSION ISCHEMIA IN EXPERIMENT [PDF]
Research Results in Pharmacology, 2016 Ischemic injury was formed in laboratory rats by applying mechanical pressure (110 mm Hg) to the anterior eye chamber for 30 minutes. The experiment revealed that the recombinant erythropoietin (50 IU/kg) prevents the development of degenerative changes ...
Anna Shabelnikova +6 more
doaj +3 more sources
Comparison of Dried Blood Spot Sampling Methods for RNA‐Based Biomarker Measurement in Anti‐Doping
Drug Testing and Analysis, Volume 18, Issue 8, Page 959-966, August 2026.This study demonstrates that RNA‐based biomarkers of erythropoiesis, ALAS2 and CA1, can be reliably quantified across commonly used DBS sampling matrices, including venous and capillary blood spotted on cellulose cards and the Tasso‐M20 device. ABSTRACT Dried blood spot (DBS) sampling offers logistical advantages, but it remains unexplored whether ...
Jacob Bejder +9 more
wiley +1 more source