Results 61 to 70 of about 16,252 (181)

Efficacy and Safety of rhIL‐11 in the Treatment of Cancer Therapy‐Induced Thrombocytopenia: A Multicenter Retrospective Study

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Objective This real‐world study aimed to investigate the cancer therapy‐induced thrombocytopenia (CTIT) profile and evaluate the efficacy and safety of recombinant human interleukin‐11 (rhIL‐11) in its management. Methods Retrospective analysis included 12,431 CTIT patients treated with rhIL‐11 across 58 Chinese centers (July 2023–June 2024 ...
Yingmei Wen, Yi Dong, Yingge Li, Jinxiong Xia, Zheming Liu, Yuanyuan Wang, Ruibin Li, Ming Wang, Bin Xu, Dongling Tang, Lulu Chen, Huibo Zhang, Qibin Song, Yi Yao   +13 more
wiley   +1 more source

De Novo Synthesis in Cancer Immunotherapy: Applications and Prospects

MedComm, Volume 7, Issue 7, July 2026.
De novo protein design creates novel structures for cancer immunotherapy, integrating rational design principles like modularity and specificity. Leveraging computational tools, it optimizes cytokine engineering, adoptive cellular therapy, and checkpoint regulation to enhance antitumor immunity.
Yang Jin, Yanfeng Wu, Jianhua Luo
wiley   +1 more source

Myeloid‐Derived Growth Factor Improves Endothelial Progenitor Cell Function and Angiogenesis in Mice With Diabetic Hindlimb Ischemia by Activating Akt/HIF‐1α Signalling Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Myeloid‐derived growth factor (MYDGF) offers new insights into inflammation and endothelial function, yet its role in endothelial progenitor cells (EPCs) and diabetes‐related hindlimb ischemia (DLI) remains unclear. In this study, we found that MYDGF depletion impaired the angiogenic function of EPCs, leading to reduced vascularisation and ...
Wen Mei, Biying Meng, Bilin Zhang, Yi Shu, Haizhao Luo, Jingwen Ye, Yijiang Hou, Biao Zhu, Jiajia Zhang   +8 more
wiley   +1 more source

ORIGINAL PAPER
Erythropoietin therapy in chronic renal failure patients prior to hemodialysis

Archives of Medical Science, 2005
The human recombinant erythropoietin (hrEpo) is crucial in anemia treatment options in chronic renal failure patients undergoing regular hemodialysis therapy.
Jacek Rysz, Piotr Bartnicki, Robert A. Stolarek   +2 more
doaj  

The stages in standardizing erythropoietin preparations

Биопрепараты: Профилактика, диагностика, лечение, 2018
Preparations of recombinant human erythropoietin (rhEPO) are included in the list of vital and essential drugs for medical use. When evaluating the quality of EPO preparations during the manufacturing process, under the state marketing authorization and ...
A. K. Yakovlev, L. A. Gayderova, N. A. Alpatova, T. N. Lobanova, T. A. Batuashvili, L. V. Simutenko, E. L. Postnova, E. I. Yurchikova   +7 more
doaj  

THE EFFECT OF ERYTHROPOIETIN SUPPLEMENTATION ON SPERM MOTILITY AND MORPHOLOGY IN WISTAR RAT AFTER LIGATION RELEASE OF THE VAS DEFERENS

Jurnal Urologi Indonesia, 2019
Objective: The patency rates after vasectomy reversal ranges from 71-97%, but there is 26-72% possibility of persistent infertility. Dysfunction or obstruction of the epididymis and oxidative stress are thought to be the important cause of male ...
Aditya Pramanta, Johan Renaldo, Doddy M Soebadi   +2 more
doaj   +1 more source

Modulation of intraabdominal organs microvessels reaction for ischemia/reperfusion by recombinant erythropoietin

Кубанский научный медицинский вестник, 2014
We investigate blood flow velocity at ischemia/reperfusion early stages and at its human recombinant erythropoietin correction. Transient hyperemia absence after ischemia/reperfusion at early stages was determined.
S. A. Alehin, M. V. Pokrovsky, L. V. Ivanova, D. P. Nazarenko, D. I. Kolmikov, L. K. Buslovskaia, I. M. Kolesnik, D. I. Pisarev   +7 more
doaj  

A Review of Pleiotropic Potential of Erythropoietin as an Adjunctive Therapy for COVID-19

Journal of Clinical and Basic Research, 2022
Coronavirus disease 2019 (COVID-19) is a severe acute respiratory disease with a high prevalence. According to the research and statistical data, in January 2021, there have been 92,262,621 confirmed cases of COVID-19 and more than two million deaths ...
Fatemeh EmamiPari, Soroush Kamali, Ghazaleh Nikzad, Narges Roosta Navi, Sanaz Soltani, Mohamad Reza Kalani   +5 more
doaj  

Advances in Analytical Methods for Erythropoietin Identification: From Clinical Use to Anti-Doping Applications

Drug Analytical Research
Erythropoietin (EPO) is an endogenous glycoprotein essential for erythropoiesis regulation and is produced mainly by the kidneys and to a lesser extent by the liver.
Matheus Betat Schafer, Bruno Pereira dos Santos , Marcelo Dutra Arbo   +2 more
doaj   +1 more source

Effect of stimulated erythropoiesis on liver SMAD signaling pathway in iron-overloaded and iron-deficient mice.

PLoS ONE, 2019
Expression of hepcidin, the hormone regulating iron homeostasis, is increased by iron overload and decreased by accelerated erythropoiesis or iron deficiency.
Jana Frýdlová, Daniel W Rogalsky, Jaroslav Truksa, Emanuel Nečas, Martin Vokurka, Jan Krijt   +5 more
doaj   +1 more source