Results 61 to 70 of about 82,538 (246)

PEGylation markedly enhances the in vivo potency of recombinant human non-glycosylated erythropoietin: A comparison with glycosylated erythropoietin

open access: yes, 2010
Recombinant human non-glycosylated erythropoietin (rh-ngEpo) expressed in E. coli was attached to polyethylene glycol (PEG) chains with different sizes and structures.
Hao, Su-Juan   +18 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Erythropoietin inhibits osteoblast function in myelodysplastic syndromes via the canonical Wnt pathway

open access: yesHaematologica, 2018
The effects of erythropoietin on osteoblasts and bone formation are controversial. Since patients with myelodysplastic syndromes often display excessively high erythropoietin levels, we aimed to analyze the effect of erythropoietin on osteoblast function
Ekaterina Balaian   +9 more
doaj   +1 more source

Protective effects of erythropoietin against cuprizone-induced oxidative stress and demyelination in the mouse corpus callosum [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Increasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of multiple sclerosis.
Iraj Ragerdi Kashani   +7 more
doaj   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

open access: yesChemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens   +3 more
wiley   +1 more source

Comprehensive Evaluation of Commercial Antibodies for High Sensitivity Detection of EPO‐Doping on Western Blots

open access: yesDrug Testing and Analysis, EarlyView.
A large‐scale evaluation of 164 commercially available anti‐human EPO antibodies was conducted to identify an alternative to clone AE7A5 anti‐EPO antibody used in doping control for the detection of erythropoiesis‐stimulating agents (ERAs) on Western blots.
Christian Reichel   +3 more
wiley   +1 more source

Erythropoietin Has Kidney Protective Efficacy beyond Stimulating Erythropoiesis

open access: yesمجله دانشکده پزشکی اصفهان, 2013
Dear Editor-in-Chief, Recently attentions have been made towards the renoprotective property of erythropoietin beyond stimulating erythropoiesis. It has been suggested that carbamylated erythropoietin administration is able to reduce cyclosporine ...
Mahmoud Rafieian-Kopaei   +2 more
doaj  

RETRACTED ARTICLE: Synergistic renoprotective effects of sesame oil and erythropoietin on ischemic kidney injury after renal transplantation

open access: yesAMB Express, 2020
In this study, we evaluated the combined therapeutic efficacy of erythropoietin (a hematopoietic hormone produced by the fetal liver and kidney in response to inflammation and apoptosis) and sesame oil (from Sesamum indicum L.) on ischemic kidney injury ...
Liyu Ye   +8 more
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

The Role of Erythropoietin as an Inhibitor of Tissue Ischemia

open access: yesInternational Journal of Biological Sciences, 2008
Erythropoietin is a hypoxia-induced cytokine that stimulates erythropoiesis through the promotion of erythroid precursor cell proliferation and differentiation.
Marios G. Lykissas, Alexandros E. Beris
doaj  

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