Results 41 to 50 of about 168,520 (319)

Recombinant human erythropoietin improves neurological outcomes in very preterm infants

Annals of Neurology, 2016
To evaluate the efficacy and safety of repeated low‐dose human recombinant erythropoietin (rhEPO) in the improvement of neurological outcomes in very preterm infants.
Juan Song, Huiqing Sun, Fa-lin Xu, W. Kang, Liang Gao, Jiajia Guo, Yanhua Zhang, Lei Xia, Xiaoyang Wang, Changlian Zhu   +9 more
semanticscholar   +1 more source

Darbepoetin alfa given every 1 or 2 weeks alleviates anaemia associated with cancer chemotherapy. [PDF]

, 2002
In part A of this study, patients were randomised to cohorts receiving darbepoetin alfa at doses of 0.5 to 8.0 m.c.g x kg(-1) x wk(-1) or to a control group receiving epoetin alfa at an initial dose of 150 U x kg(-1) three times weekly.
Armstrong, S, Colowick, AB, Glaspy, JA, Jadeja, JS, Justice, G, Kessler, J, O'Byrne, J, Richards, D, Rossi, G, Schwartzberg, L, Tchekmedyian, NS   +10 more
core   +2 more sources

Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution

Nature Communications, 2016
Inflammation resolution is an active process, the failure of which causes uncontrolled inflammation which underlies many chronic diseases. Therefore, endogenous pathways that regulate inflammation resolution are fundamental and of wide interest. Here, we
Bangwei Luo, Jinsong Wang, Zongwei Liu, Zi-gang Shen, Rongchen Shi, Yu-qi Liu, Yu Liu, Man Jiang, Yuzhang Wu, Zhiren Zhang   +9 more
semanticscholar   +1 more source

Use of Recombinant Human Erythropoietin in Renal Anemia in Children

Bangabandhu Sheikh Mujib Medical University Journal, 2009
Erythropoietin is a hormone highly effective as like as natural erythropoietin to maintain target hemoglobin and hematocrit level in renal anemia. Its advantage over blood transfusion has been proved by improving the quality of life and decreasing ...
Habibur Rahman, Salma Jahan, Afroza Begum, Golam Muinuddin, MM Hossain   +4 more
doaj   +1 more source

Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer : randomized clinical trial [PDF]

, 2013
BACKGROUND: The AGO-ETC trial compared 5-year relapse-free survival of intense dose-dense (IDD) sequential chemotherapy with epirubicin (E), paclitaxel (T), and cyclophosphamide (C) (IDD-ETC) every 2 weeks vs conventional scheduled epirubicin ...
Bois, Andreas du, Hinke, Axel, Huober, Jens, Jackisch, Christian, Kreienberg, Rolf, Kuhn, Walther, Kurbacher, Christian, Lueck, Hans-Joachim, Moebus, Volker, Nitz, Ulrike, Runnebaum, Ingo B., Schneeweiss, Andreas, Thomssen, Christoph, Untch, Michael   +13 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor

Disease Models & Mechanisms, 2013
SUMMARY There is limited evidence that the tissue-protective effects of erythropoietin are mediated by a heterocomplex of the erythropoietin receptor and the β-common receptor (‘tissue-protective receptor’), which is pharmacologically distinct from the ...
Areeg I. Khan, Sina M. Coldewey, Nimesh S. A. Patel, Mara Rogazzo, Massimo Collino, Muhammed M. Yaqoob, Peter Radermacher, Amar Kapoor, Christoph Thiemermann   +8 more
doaj   +1 more source

Erythropoietin Pathway: A Potential Target for the Treatment of Depression

International Journal of Molecular Sciences, 2016
During the past decade, accumulating evidence from both clinical and experimental studies has indicated that erythropoietin may have antidepressant effects.
Chongyang Ma, F. Cheng, Xueqian Wang, Changming Zhai, Wenchao Yue, Yajun Lian, Qingguo Wang   +6 more
semanticscholar   +1 more source

Dissociation of Erythropoietin from Erythropoietin-Antierythropoietin Complex

Experimental Biology and Medicine, 1971
SummaryThe biological activity of human urinary erythropoietin is completely neutralized when combined with serum from rabbits immunized with erythropoietin. Acidification to pH 5.0, followed by heating in a boiling water bath for 5 min, recovers essentially all the erythropoietic biological activity from such a combination.
Garcia, J F, Schooley, J C
openaire   +3 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source