Cold Spring Harbor Perspectives in Medicine, 2013 During the past century, few proteins have matched erythropoietin (Epo) in capturing the imagination of physiologists, molecular biologists, and, more recently, physicians and patients. Its appeal rests on its commanding role as the premier erythroid cytokine, the elegant mechanism underlying the regulation of its gene, and its remarkable impact as a ...
openaire +2 more sources
Macrophages as novel target cells for erythropoietin
Haematologica, 2010 Background Our original demonstration of immunomodulatory effects of erythropoietin in multiple myeloma led us to the search for the cells in the immune system that are direct targets for erythropoietin.
Lilach Lifshitz +4 more
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Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care [PDF]
, 2012 Author can archive publisher's pdf. Free via Creative Commons: CC-BENCHTOBEDSIDE-2.0.
Nandra, KK, Patel, NSA, Thiemermann, C
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Neuronal damage after moderate hypoxia and erythropoietin
Neurobiology of Disease, 2005 Both mild hypoxia and exogenous erythropoietin may protect the brain against subsequent severe hypoxia, and the conditioning effect of transient hypoxia is partly mediated by hypoxia-induced endogenous erythropoietin.
Astrid Weber +8 more
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Prognostic significance of endogenous erythropoietin in long-term outcome of patients with acute decompensated heart failure [PDF]
, 2016 Aims Although previous reports suggest that an elevated endogenous erythropoietin (EPO) level is associated with worse clinical outcomes in chronic heart failure (HF) patients, the prognostic implication of EPO in patients with acute decompensated HF ...
Anand +27 more
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Low oxygen tension primes aortic endothelial cells to the reparative effect of tissue-protective cytokines [PDF]
, 2015 Erythropoietin (EPO) has both erythropoietic and tissue-protective properties. The EPO analogues carbamylated EPO (CEPO) and pyroglutamate helix B surface peptide (pHBSP) lack the erythropoietic activity of EPO but retain the tissue-protective properties
A Anagnostou +57 more
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Initiating haemodialysis twice-weekly as part of an incremental programme may protect residual kidney function [PDF]
, 2018 © The Author(s) 2018. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.Background: Initiating twice-weekly haemodialysis (2×HD) in patients who retain significant residual kidney function (RKF) may have benefits.
Busby, Amanda D +7 more
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Anesthesia and Analgesia, 2019 BACKGROUND: Erythropoietic-stimulating agents such as erythropoietin have been used as part of patient blood management programs to reduce or even avoid the use of allogeneic blood transfusions.
Brian C. Cho +6 more
semanticscholar +1 more source
Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]
, 2003 Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Bieber +36 more
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Erythropoietin modulates bone marrow stromal cell differentiation
Bone Research, 2019 Erythropoietin is essential for bone marrow erythropoiesis and erythropoietin receptor on non-erythroid cells including bone marrow stromal cells suggests systemic effects of erythropoietin. Tg6 mice with chronic erythropoietin overexpression have a high
S. Suresh +4 more
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