Use of Recombinant Human Erythropoietin in Renal Anemia in Children [PDF]
Erythropoietin is a hormone highly effective as like as natural erythropoietin to maintain target hemoglobin and hematocrit level in renal anemia. Its advantage over blood transfusion has been proved by improving the quality of life and decreasing ...
Habibur Rahman +4 more
doaj +2 more sources
Safety and Short-term Outcomes of High-Dose Erythropoietin in Preterm Infants With Intraventricular Hemorrhage: The EpoRepair Randomized Clinical Trial. [PDF]
IMPORTANCE Intraventricular hemorrhage (IVH) is a major cause of neonatal morbidity and mortality in preterm infants without a specific medical treatment to date. OBJECTIVE To assess the safety and short-term outcomes of high-dose erythropoietin
Held, L. +21 more
core +4 more sources
Oxygen-dependent erythropoietin production by the isolated perfused rat kidney [PDF]
In this study we have investigated the role of oxygen delivery and of classic second messengers on erythropoietin production by the isolated perfused rat kidney. We found that the rat kidney was capable of de novo synthesis of erythropoietin.
Scholz, Holger +9 more
core +1 more source
Evaluation of the stability of human erythropoietin in samples for radioimmunoassay [PDF]
Radioimmunoassays for erythropoietin are limited so far to a few specialized laboratories and this requires transport and storage of samples. We therefore tested the stability of immunoreactive erythropoietin in serum and plasma samples obtained from a ...
Kurtz, Armin +5 more
core +1 more source
Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure [PDF]
The pharmacokinetic profile of recombinant human erythropoietin (rHuEpo) was studied after a single intravenous dose of 150 U/kg in ten patients with various degrees of renal function: group I, creatinine clearance greater than 80 ml/min, n = 2; group II,
K. Jandeleit +18 more
core +1 more source
Erythropoiesis, serum erythropoietin, and serum IGF-I in rats during accelerated growth [PDF]
In this study we have examined the correlation between activity of erythropoiesis and serum concentrations of erythropoietin and insulin-like growth factor I in male and female rats during accelerated growth (day 30-90).
Kurtz, Armin +11 more
core +1 more source
Rate of erythropoietin formation in humans in response to acute hypobaric hypoxia [PDF]
This study was carried out to investigate the early changes in erythropoietin (EPO) formation in humans in response to hypoxia. Six volunteers were exposed to simulated altitudes of 3,000 and 4,000 m in a decompression chamber for 5.5 h. EPO was measured
Kurtz, Armin +17 more
core +1 more source
Neuronal damage after moderate hypoxia and erythropoietin
Both mild hypoxia and exogenous erythropoietin may protect the brain against subsequent severe hypoxia, and the conditioning effect of transient hypoxia is partly mediated by hypoxia-induced endogenous erythropoietin.
Astrid Weber +8 more
doaj +1 more source
A 45 min bout of hot-water immersion induces transient plasma volume contraction without a detectable increase in circulating erythropoietin. [PDF]
Abstract Heat acclimation is increasingly used to induce haematological adaptations and enhance endurance performance. Although repeated hot‐water immersion (HWI) has been shown to increase haemoglobin mass, the acute physiological responses that might underpin these longer‐term adaptations remain poorly understood.
Zerilli O +6 more
europepmc +2 more sources
Increased plasma viscosity as a reason for inappropriate erythropoietin formation [PDF]
The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or ...
A Zimmermann +23 more
core +1 more source

