Coping with hypoxemia: Could erythropoietin (EPO) be an adjuvant treatment of COVID-19?
Highlights • Epidemiological data suggests that the physiological mechanisms underlying highaltitude.• acclimatization may provide possible avenues to identify therapeutic targets for prophylaxis and treatment of COVID-19.• Acute mountain sickness (AMS ...
J. Soliz +9 more
semanticscholar +1 more source
Haemoglobin mass and running time trial performance after recombinant human erythropoietin administration in trained men [PDF]
<p>Recombinant human erythropoietin (rHuEpo) increases haemoglobin mass (Hbmass) and maximal oxygen uptake (v˙ O2 max).</p> <p>Purpose: This study defined the time course of changes in Hbmass, v˙ O2 max as well as running time trial ...
A Lucia +51 more
core +7 more sources
Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease. [PDF]
Erythropoietin is a growth factor commonly used to manage anemia in patients with chronic kidney disease. A significant clinical challenge is relative resistance to erythropoietin, which leads to use of successively higher erythropoietin doses, failure ...
Eliyahu V Khankin +5 more
doaj +1 more source
Preoperative anemia is a common finding. Preoperative allogeneic transfusion, iron therapy, vitamin supplementation and erythropoietin therapy are the current management strategies for preoperative anemia.
Sheikh Muhammad Ebad Ali +5 more
doaj +1 more source
Evaluation of the stability of human erythropoietin in samples for radioimmunoassay [PDF]
Radioimmunoassays for erythropoietin are limited so far to a few specialized laboratories and this requires transport and storage of samples. We therefore tested the stability of immunoreactive erythropoietin in serum and plasma samples obtained from a ...
Bauer, Christian +5 more
core +1 more source
Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation [PDF]
This study was done to investigate aspects of control of extrarenal erythropoietin (Ep) production. To this end we studied the effects of three stimuli of renal Ep production in the adult, i.e.
Bauer, Christian +4 more
core +1 more source
Pharmacokinetics of recombinant human erythropoietin applied subcutaneously to children with chronic renal failure [PDF]
The single-dose pharmacokinetics of recombinant human erythropoietin (rHuEPO) given SC was investigated in 20 patients aged 7-20 years at different stages of chronic renal failure.
Braun, A. +5 more
core +1 more source
Primary familial and congenital polycythemia is characterized by erythropoietin hypersensitivity of erythroid progenitors due to germline nonsense or frameshift mutations in the erythropoietin receptor gene.
Florence Pasquier +11 more
doaj +1 more source
Serum Erythropoietin in Patients with Chronic Renal Failure in the Predialysis Stage [PDF]
A prospective study was carried out of serum erythropoietin levels in patients with chronic renal failure/chronic kidney disease in the predialysis period. The study is part of scientific project № 2/2022, financed by Medical University-Pleven.
Adelaida Ruseva +5 more
doaj +3 more sources
Oxygen-dependent expression of the erythropoietin gene in rat hepatocytes in vitro [PDF]
Since in juvenile rats the liver is the predominant site of erythropoietin (EPO) gene expression, we have used primary cultures of juvenile rat hepatocytes to establish and in vitro system for investigation of oxygen-dependent EPO formation.
Eckardt, Kai-Uwe +3 more
core +1 more source

