Results 171 to 180 of about 408,399 (236)

Beyond intelligence: Exploring the role of growth mindsets in the domain of social–emotional skills

open access: yesBritish Journal of Educational Psychology, EarlyView.
Abstract Background Growth mindsets refer to the belief that personal attributes can be developed and improved through learning and effort. Much of the prior work on mindsets has focused on mindsets of intelligence, with little attention devoted to whether and how growth mindsets might also be relevant to the domain of social–emotional skills.
Jianhua Zhang   +2 more
wiley   +1 more source

CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis. [PDF]

open access: yesCell Death Dis
Li D   +14 more
europepmc   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

open access: yesBritish Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska   +2 more
wiley   +1 more source

Association between insulin resistance and sudomotor dysfunction in adults with type 1 diabetes. [PDF]

open access: yesEndocr Connect
Gandecka-Pempera A   +4 more
europepmc   +1 more source

Pembrolizumab for Early‐Stage Triple‐Negative Breast Cancer: KEYNOTE‐522 Japan Subgroup Analysis

open access: yesCancer Science, EarlyView.
In the global, phase 3 KEYNOTE‐522 study of high‐risk early‐stage triple‐negative breast cancer (TNBC), neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab improved efficacy outcomes versus neoadjuvant chemotherapy alone. In this analysis of Japanese participants from KEYNOTE‐522, neoadjuvant pembrolizumab plus chemotherapy ...
Masato Takahashi   +16 more
wiley   +1 more source

Evolutionary Analysis of Transcriptional Regulation Mediated by Cdx2 in Rodents

open access: yesCell Proliferation, EarlyView.
Our study (1) represented a first systematic analysis of species‐specific adaptation in the DNA binding pattern of transcription factor; (2) represented a first study of cis‐regulation between two reproductively isolated species by using a novel allodiploid system; (3) demonstrated a higher conservation of transcriptional output than that of DNA ...
Weizheng Liang   +13 more
wiley   +1 more source

Association of Shock Index and Variants with Mortality in Acute Pulmonary Embolism. [PDF]

open access: yesWest J Emerg Med
Upchurch CP   +4 more
europepmc   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

open access: yesCell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao   +7 more
wiley   +1 more source

Ethical and Regulatory Considerations in the Clinical Translation of Pluripotent Stem Cell‐Derived NK Cell Therapies

open access: yesCell Proliferation, EarlyView.
Advancements in the generation of human pluripotent stem cell‐derived natural killer (PSC‐NK) cells have attracted considerable attention within the biomedical research community, offering a promising off‐the‐shelf technique for universal immune therapy.
Qianwen Chen   +5 more
wiley   +1 more source

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