Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [PDF]
The POU domain transcription factor OCT4 is a key regulator of pluripotency in the early mammalian embryo and is highly expressed in the inner cell mass of the blastocyst. Consistent with its essential role in maintaining pluripotency, Oct4 expression is
Adjaye, J. +8 more
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Correlations of bile acids in the bile of rats in conditions of alloxan induced diabetes melitus [PDF]
The ratio of bile acids in the bile of rats with alloxan diabetes was investigated using the method of thin-layer chromatography. Changes of coefficients of conjugation and hydroxylation of bile acids were calculated and analyzed in half-hour samples of ...
N. N. Danchenko +2 more
doaj +1 more source
Cell-free Embryonic Stem Cell Extract-mediated Derivation of Multi-potent Stem Cells from NIH3T3 Fibroblasts for Functional and Anatomical Ischemic Tissue Repair [PDF]
The oocyte-independent generation of multipotent stem cells is one of the goals in regenerative medicine. We report that upon exposure to mouse ES cell (ESC) extracts, reversibly permeabilized NIH3T3 cells undergo de-differentiation followed by stimulus ...
Deepali Ahluwalia +13 more
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Physiological monitoring in the complex multi-morbid heart failure patient - Introduction. [PDF]
Repeated physiological monitoring of comorbidities in heart failure (HF) is pivotal. This document introduces the main challenges related to physiological monitoring in the complex multimorbid HF patient, arising during an ESC consensus meeting on this ...
Rosano, GMC, Seferović, PM
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Methods for improving accuracy of the dementia diagnosis using feature dimension reduction
In this paper, the problem of choosing the right feature for diagnosing Dementia is discussed. Several features that could affect dementia were reviewed and their importance was evaluated.
Maryam Naderan, Yuriy P. Zaychenko
doaj +1 more source
The effect of melanin on the proteolytic potential of blood under alkali esophageal burn
Caustic esophageal burns are among serious medical problems of global significance. Due to a key role in biological processes proteolytic enzymes actively involved in the pathological mechanisms underpinning the development and progression of burn ...
Nataliia Chornenka +9 more
doaj +1 more source
ESC NN-Potentials in Momentum Space. I. PS-PS Exchange Potentials [PDF]
A momentum space representation is derived for the Nijmegen Extended-Soft-Core (ESC) interactions. The partial wave projection of this representation is carried through, in principle for Two-Meson-Exchange (TME) in general.
A. Klein +24 more
core +2 more sources
Evolution of unconditional dispersal in periodic environments
Organisms modulate their fitness in heterogeneous environments by dispersing. Prior work shows that there is selection against "unconditional" dispersal in spatially heterogeneous environments.
Li, Chi-Kwong, Schreiber, Sebastian J.
core +1 more source
Differences in clinical characteristics and 1-year outcomes of hospitalized patients with heart failure in ESC-HF Pilot and ESC-HF-LT registries [PDF]
[Abstract] INTRODUCTION The management of heart failure (HF) has changed significantly in recent decades. OBJECTIVES We analyzed the clinical profile, 1‑year outcomes, predictors of mortality, and hospital readmissions in hospitalized patients enrolled ...
Balsam, Pawel +11 more
core +2 more sources
On the geometry of a proposed curve complex analogue for $Out(F_n)$ [PDF]
The group $\Out$ of outer automorphisms of the free group has been an object of active study for many years, yet its geometry is not well understood. Recently, effort has been focused on finding a hyperbolic complex on which $\Out$ acts, in analogy with ...
Sabalka, Lucas, Savchuk, Dmytro
core

