Bacteriophage–derived double-stranded RNA (larifan) exerts variable effects on human blood monocytes depending on age and sex of donors [PDF]
To date, great attention is paid to sex and age differences in the therapeutic effectiveness of drugs, including those that impact the immune system.
R. Dovhyi +7 more
doaj +1 more source
Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants [PDF]
Mutations and inadequate methylation profiles of CITED2 are associated with human congenital heart disease (CHD). In mouse, Cited2 is necessary for embryogenesis, particularly for heart development, and its depletion in embryonic stem cells (ESC) impairs
AC Fahed +45 more
core +1 more source
Blocking Former Sex Offenders from Online Social Networks: Is this a Due Process Violation? [PDF]
Extremum seeking control (ESC) is a classical adaptive control method aimed at locating and tracking optimal operating conditions in complex non-linear plants. Early results on ESC were restricted to plants that could bedescribed by Wiener or Hammerstein
Hines, Nichole
core +1 more source
The sources that reionized the universe are still unknown, but likely candidates are faint but numerous galaxies. In this paper we present results from running a high resolution, uniform volume simulation, the Vulcan, to predict the number densities of ...
Anderson, Lauren +4 more
core +1 more source
The Spectral Slope and Escape Fraction of Bright Quasars at $z \sim 3.8$: the Contribution to the Cosmic UV Background [PDF]
We use a sample of 1669 QSOs ...
Cristiani, Stefano +5 more
core +2 more sources
On the Low Energy Decrease in Galactic Cosmic Ray Secondary/Primary Ratios [PDF]
Galactic cosmic ray (GCR) secondary/primary ratios such as B/C and (Sc+Ti+V)/Fe are commonly used to determine the mean amount of interstellar material through which cosmic rays travel before escaping from the Galaxy (Λ_(esc)).
Binns, W. R. +10 more
core +1 more source
Rare events in population genetics: Stochastic tunneling in a two-locus model with recombination
We study the evolution of a population in a two-locus genotype space, in which the negative effects of two single mutations are overcompensated in a high fitness double mutant.
Alexander Altland +6 more
core +1 more source
‘Anthropomorphic drones’ and colonized bodies: William Gibson’s the peripheral [PDF]
William Gibson tends to write in trilogies, as his first nine novels show. These series – the Sprawl, the Bridge, and the Blue Ant trilogies – are set in three different time periods and are populated by characters who reappear from one book to the next.
Mcfarlane, Anna
core +1 more source
Light $\Xi$ hypernuclei in four-body cluster models [PDF]
Detailed structure calculations in $^{\: 12}_{\Xi^-}$Be, $^{\: 5}_{\Xi^-}$H, $^{\: 9}_{\Xi^-}$Li, $^{\: 7}_{\Xi^-}$H and $^{\:10}_{\Xi^-}$Li are performed within the framework of the microscopic two-, three- and four-body cluster models using the ...
Hiyama, E. +4 more
core +2 more sources
C(60) fullerene effect on the functional activity of rat gastrocnemius muscle during its regeneration after the open injury [PDF]
Open injuries are one of the most common skeletal muscle traumas. The study aimed to estimate the effect of the oral administration of C60 fullerene aqueous solution (C60FAS) daily at a dose of 1 mg/kg on the restoration of rat skeletal muscle functional
D. M. Nozdrenko +7 more
doaj +1 more source

