Results 101 to 110 of about 804,660 (312)

Role of Viral Envelope Proteins in Determining Susceptibility of Viruses to IFITM Proteins

open access: yesViruses
Interferon-induced transmembrane proteins (IFITMs) are a family of proteins which inhibit infections of various enveloped viruses. While their general mechanism of inhibition seems to be non-specific, involving the tightening of membrane structures to ...
Thomas Marceau, Martine Braibant
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

An escape into fiction [PDF]

open access: yesScience, 2019
I arrived home from work, my mind racing. I was scheduled to perform an experiment using a pricey piece of equipment—one that I'd be unlikely to gain much access to again during my Ph.D.—and I needed it to go flawlessly. “Will the x-rays transmit correctly?” I wondered.
openaire   +2 more sources

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

open access: yesNature, 2021
D. Planas   +31 more
semanticscholar   +1 more source

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

open access: yesScience Translational Medicine, 2012
Activated tumor-infiltrating lymphocytes may induce B7-H1 on melanocytes, which suggests adaptive resistance to antitumor immunity. The Great Escape In the movie The Great Escape, “problem” prisoners with multiple escape attempts are put in an “escape ...
J. Taube   +10 more
semanticscholar   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier   +3 more
wiley   +1 more source

Escaping the loop [PDF]

open access: yesQJM: An International Journal of Medicine, 2004
This is a story about intuition and its relation to logic. A mother came to see me recently with her nine-year-old son, who wets his bed. She wanted me to write a letter to the council to support the family's application for a bigger flat. The boy apparently has two elder brothers who share his bedroom.
openaire   +2 more sources

Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane   +3 more
wiley   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

open access: yesAdvanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios   +5 more
wiley   +1 more source

The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery.

open access: yesBioconjugate chemistry, 2018
Many emerging therapies rely on the delivery of biological cargo into the cytosol. Nanoparticle delivery systems hold great potential to deliver these therapeutics but are hindered by entrapment and subsequent degradation in acidic compartments of the ...
Samuel A. Smith   +3 more
semanticscholar   +1 more source

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