Results 151 to 160 of about 488,546 (268)
Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic
Advanced Robotics Research, EarlyView.Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang +5 more
wiley +1 more source
Therapy-induced immunoediting and the evolution of cancer immune escape. [PDF]
Front ImmunolMeng S, Wang Z.
europepmc +1 more source
Origami‐Inspired Morphing Fuselage for Agile Fixed‐Wing Flight
Advanced Robotics Research, EarlyView.Conventional aircraft steer with rigid control surfaces. SoAR instead replaces the fuselage itself with a cable‐driven origami continuum body that bends in 3D and compresses on demand. Whole‐fuselage morphing steers fixed‐wing flight: achieving sharp, near‐zero‐radius turns and rapid braking without ailerons, rudder, or elevator, while the same ...
Abudula Aihaitijiang, Cagdas D. Onal
wiley +1 more source
Advanced Robotics Research, EarlyView.A balanced multimodal food‐waste dataset and a novel Split Spatial‐Spectral Attention fusion framework are presented for robotic contaminant detection. Separate processing of RGB, thermal, and multispectral inputs preserves subtle material signatures before feature integration, reducing modality interference and improving classification and ...
Matthew Vestal +5 more
wiley +1 more source
XeraBorg: Neural Control of Tail‐Flick Escape for Backward Propulsion in Cyborg Crayfish
Advanced Robotics Research, EarlyView.This work presents the first controlled tail‐flick propulsion method for the cyborg Cherax quadricarinatus. Comprehensive experiments establish a foundational framework for using the crayfish's natural escape mechanism as a locomotion strategy, expanding its potential as an underwater and amphibious mobile robot.
H. Nhan Le +7 more
wiley +1 more source
Stimulus-Responsive Polymeric Carriers for Gene Delivery: Balancing Endosomal Escape with Nucleic Acid Release. [PDF]
Pharm ResHulugalla K +3 more
europepmc +1 more source
Advanced Science, EarlyView.Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García +13 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
Cancer immunoediting in the melanoma tumor microenvironment: from immune elimination to therapeutic resistance. [PDF]
Front ImmunolYan X, Zhang Q, Chen Z, Zhou H.
europepmc +1 more source
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source