Results 161 to 170 of about 621,777 (315)

Combining machine learning and iterative experiments to keep pace with emerging viral variants of concern. [PDF]

open access: yesPLoS Comput Biol
Sheffield T   +5 more
europepmc   +1 more source

Escaping Sonder [PDF]

open access: yesJournal of Pain and Symptom Management, 2018
openaire   +2 more sources

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei   +11 more
wiley   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

Homenatge a Vicente Folch Godes, "Escape". Entrevista a Vicente Claramonte

open access: yes, 1872
Homenatge a Vicente Folch Godes, "Escape", secretari de l'Automòbil Club, 8-4-1972.
Vicent Doménech, Francesc "Quiquet de Castàlia"   +2 more
core  

Novel examples of NMD escape through alternative intronic polyadenylation. [PDF]

open access: yesNAR Genom Bioinform
Vlasenok M   +4 more
europepmc   +1 more source

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

open access: yesAdvanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang   +15 more
wiley   +1 more source

Escape from Hell The True Story of the Auschwitz Protocol

open access: yes
Escape from Hell -- Contents -- Foreword -- Introduction -- Chapter 1. Just for Work -- Chapter 2. Work - German Style -- Chapter 3. An Exalted VisitA -- Chapter 4. An Even More Exalted Visit -- Chapter 5. The Ceremonial -- Chapter 6.
Wetzler, Alfréd.
core  

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