Results 61 to 70 of about 1,655 (217)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Nosema ceranae escapes fumagillin control in honey bees.

open access: yesPLoS Pathogens, 2013
Fumagillin is the only antibiotic approved for control of nosema disease in honey bees and has been extensively used in United States apiculture for more than 50 years for control of Nosema apis.
Wei-Fone Huang   +3 more
doaj   +1 more source

Escape boxes: Bringing escape room experience into the classroom

open access: yesBritish Journal of Educational Technology, 2020
Abstract In this paper, we present an escape box as a means to introduce the escape room concept into classrooms. Recreational escape rooms have inspired teachers all over the world to adapt the popular entertainment activity for education.
Alice Veldkamp   +5 more
openaire   +4 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Elizabeth Spencer’s Spacious Escapes

open access: yesJournal of the Short Story in English, 2019
Dans la fiction brève d’Elizabeth Spencer, les portes, les fenêtres et les regards accidentels ne sont pas seulement des images récurrentes ; ce sont des indices, pour les personnages et les lecteurs, pour apprendre à vivre.
Amy Weldon
doaj  

Site-Specific Treatment of Late-Season Weed Escapes in Rice Utilizing a Remotely Piloted Aerial Application System

open access: yesWeed Technology
Drone technology and digital image analysis have enabled significant advances in precision agriculture, especially in site-specific treatment of weed escapes in crop fields.
Bholuram Gurjar   +8 more
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

An escape into fiction [PDF]

open access: yesScience, 2019
I arrived home from work, my mind racing. I was scheduled to perform an experiment using a pricey piece of equipment—one that I'd be unlikely to gain much access to again during my Ph.D.—and I needed it to go flawlessly. “Will the x-rays transmit correctly?” I wondered.
openaire   +2 more sources

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