Results 131 to 140 of about 495,730 (356)

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Genomic characterization of antibiotic resistant Escherichia coli isolated from domestic chickens in Pakistan [PDF]

, 2019
Poultry husbandry is important for the economic health of Pakistan, but the Pakistani poultry industry is negatively impacted by infections ...
Abbas, Muhammad Athar, Ali Malik, Akbar, Ali, Naeem, Burnham, Carey-Ann D, D\u27Souza, Alaric W, Dantas, Gautam, Ferreiro, Aura, Potter, Robert F, Rafique, Muhammad, Rahim, Abdul, Siddique, Naila, Wallace, Meghan A   +11 more
core   +1 more source

Dogs Can Be Reservoirs of Escherichia coli Strains Causing Urinary Tract Infection in Human Household Contacts [PDF]

, 2023
Peter Damborg, Mattia Pirolo, Laura Schøn Poulsen, Niels Frimodt‐Møller, Luca Guardabassi   +4 more
openalex   +1 more source

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Protective effect of SARS-CoV-2 preventive measures against ESKAPE and Escherichia coli infections. [PDF]

Eur J Clin Invest, 2021
Gaspari R, Spinazzola G, Teofili L, Avolio AW, Fiori B, Maresca GM, Spanu T, Nicolotti N, De Pascale G, Antonelli M.   +9 more
europepmc   +1 more source

Comparison ofEscherichia coliStrains Recovered from Human Cystitis and Pyelonephritis Infections in Transurethrally Challenged Mice [PDF]

, 1998
David E. Johnson, C. Virginia Lockatell, Robert G. Russell, J. Richard Hebel, M D Island, Ann E. Stapleton, Walter E. Stamm, John W. Warren   +7 more
openalex   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens. [PDF]

Microbiol Spectr, 2022
Helmy YA, Kathayat D, Deblais L, Srivastava V, Closs G, Tokarski RJ, Ayinde O, Fuchs JR, Rajashekara G.   +8 more
europepmc   +1 more source

DNA‐Inspired Multi‐Functional Double‐Cross‐Linking Self‐Healing Hydrogel Promotes the Healing of Diabetic Wounds

Advanced Science, EarlyView.
A self‐healing hydrogel crosslinked with dynamic nucleobase‐mimetic bonds delivers curcumin‐loaded exosomes. It promotes diabetic wound healing via a synergistic combination of antibacterial, anti‐inflammatory, pro‐angiogenic, and immunomodulatory mechanisms, providing a comprehensive therapeutic approach.
Pu Yang, Yue Hu, Yikun Ju, Naihsin Hsiung, Juyi Ye, Anquan Jian, Lanjie Lei, Bairong Fang   +7 more
wiley   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source