Results 221 to 230 of about 1,005,431 (399)

Effectiveness of fosfomycin trometamol as oral step-down therapy for bacteraemic urinary tract infections due to MDR Escherichia coli: a post hoc analysis of the FOREST randomized trial [PDF]

open access: hybrid, 2023
Jesús Sojo-Dorado   +26 more
openalex   +1 more source

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du   +5 more
wiley   +1 more source

Hamburger-associated Escherichia coli O157:H7 infection in Las Vegas: a hidden epidemic.

open access: green, 1997
P R Cieslak   +11 more
openalex   +2 more sources

Escherichia coliO157 Infection and Secondary Spread, Scotland, 1999–2008 [PDF]

open access: diamond, 2011
Mary E. Locking   +5 more
openalex   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

open access: yesAdvanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu   +8 more
wiley   +1 more source

Clinical and Molecular Epidemiology of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Infections in Metro Detroit: Early Dominance of the ST-131 Clone. [PDF]

open access: yesInfect Dis Ther, 2020
Mills JP   +9 more
europepmc   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

open access: yesAdvanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li   +17 more
wiley   +1 more source

Rapid formulation of a genetically diverse phage cocktail targeting uropathogenic Escherichia coli infections using the UTI89 model. [PDF]

open access: yesSci Rep
Kongsomboonchoke P   +6 more
europepmc   +1 more source

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