Results 81 to 90 of about 308,274 (302)

Towards the application of Lactococcus lactis-based oral vaccines in porcine disease control

open access: yes, 2012
C
Loos, Michaela   +5 more
core  

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun   +15 more
wiley   +1 more source

Antibacterial activity of Tribulus terrestris methanol extract against clinical isolates of Escherichia coli

open access: yesHerba Polonica, 2016
Introduction:Tribulus terrestris L. is traditionally used for treatment of urinary tract infections. Escherichia coli, as the most prominent agent of urinary tract infections, can be sensitive to T. terrestris extract.
Batoei Sara   +2 more
doaj   +1 more source

High rates of multidrug resistance among uropathogenic Escherichia coli in children and analyses of ESBL producers from Nepal

open access: yesAntimicrobial Resistance and Infection Control, 2017
Background Emergence of Extended-spectrum beta-lactamase producing Escherichia coli causing urinary tract infections (UTI) among pediatric patients is an increasing problem worldwide. However, very little is known about pediatric urinary tract infections
Narayan Prasad Parajuli   +6 more
doaj   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu   +5 more
wiley   +1 more source

The Relationship between Phylogenetic Groups and Pathogenicity Encoding Genes with regards to Extra-Intestinal Escherichia coli Isolates’ Factors using Multiplex-PCR Method

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Extraintestinal Escherichia coli bacteria is the main reason behind the urogenital infections in humans. Several virulence factors such as cytotoxin genes coding for proteins, adhesion, siderophore receptors and outer-membrane ...
Ahmad Rashki, Hosseiali Abdi
doaj  

A review of colistin-resistant Escherichia coli isolates in the Middle East: mechanisms, epidemiology, and dissemination from different sources in humans, animals, foodand soil [PDF]

open access: yesArchives of Razi Institute
Escherichia coli is a normal gut inhabitant, that is able to cause various diseases such as enteric, urinary tract, cystitis, and systemic infections in humans and animals.
Sara Rahimi   +3 more
doaj   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao   +9 more
wiley   +1 more source

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