Results 161 to 170 of about 75,719 (266)

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

open access: yesThe FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano   +10 more
wiley   +1 more source

Optimized bacterial expression of a synthetic BRIL antibody. [PDF]

open access: yesActa Crystallogr F Struct Biol Commun
Cooper BF, Isom GL.
europepmc   +1 more source

Structural and thermodynamic analyses of a novel β‐1,2‐glucan binding mode in the ABC transporter solute‐binding protein Chy400_4166 from Chloroflexus aurantiacus

open access: yesThe FEBS Journal, EarlyView.
Cyclic β‐1,2‐glucan (CβG)‐associated solute‐binding protein of type I ABC transporter was originally identified in Chloroflexus aurantiacus, a phototrophic bacterium. Crystal structures in complex with CβGs revealed unique binding modes that are fundamentally distinct from that of the short β‐1,2‐glucooligosaccharides‐binding protein.
Kazuya Kato   +6 more
wiley   +1 more source

Coniferyl aldehyde from the phenylpropanoid pathway targets pyruvate kinase in Dactylobotrys graminicola to confer sheath rot resistance in hulless barley

open access: yesJournal of Integrative Plant Biology, EarlyView.
Hulless barley resists the newly identified sheath rot disease caused by the necrotrophic fungal pathogen Dactylobotrys graminicola by releasing coniferyl aldehyde, a natural compound that disrupts energy production in the fungus. ABSTRACT Dactylobotrys graminicola (Dgr), a necrotrophic fungal pathogen, has recently been identified as the causative ...
Haowen Zheng   +12 more
wiley   +1 more source

Built different: ER cisternae formed by the Arabidopsis Lunapark proteins differ in ultrastructure and affect ER–Golgi transport

open access: yesNew Phytologist, EarlyView.
The endoplasmic reticulum (ER) is a key structure in plant cells that helps produce and transport proteins. We discovered that different Lunapark proteins shape ER structures in distinct ways, affecting protein movement and secretion. Understanding how ER structure influences function can help improve plant‐based production of valuable compounds, such ...
Charlotte Pain   +9 more
wiley   +1 more source

A Non‐Host Pathogen Elicitor Induces Blast Resistance Mediated by OsNAC78‐Pir7b Module in Rice

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plants exhibit broad‐spectrum and persistent resistance induced by non‐host pathogens. Previous studies have found that syringolin A secreted by Pseudomonas syringae pv. syringae can activate the expression of defense‐related gene Pir7b in non‐host rice, but the underlying mechanism remains ambiguous.
Yunjie Xie   +11 more
wiley   +1 more source

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