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Overview of the immunomodulatory role of bacterial probiotic-derived peptidoglycan: from molecular insights to therapeutic application [PDF]
Frontiers in MicrobiologyProbiotics are well recognized for their ability to modulate host immune responses; however, growing evidence indicates that many of their beneficial effects are mediated by structural components rather than by viable microorganisms.
Omer Qutaiba B. Allela +5 more
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Recent Advances in Peptidoglycan Synthesis and Regulation in Bacteria
Biomolecules, 2023 Bacteria must synthesize their cell wall and membrane during their cell cycle, with peptidoglycan being the primary component of the cell wall in most bacteria.
Anne Galinier +2 more
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Multilevel Regulation of Peptidoglycan Dynamics in Bacteria: From Molecular Mechanisms to Applied Perspectives [PDF]
BiomoleculesPeptidoglycan, a crucial constituent of the bacterial cell envelope, is essential for maintaining cellular integrity and morphology. Elucidating the regulatory processes that coordinate its biosynthesis and turnover not only addresses a fundamental ...
Chang Dong +4 more
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Characterization of the cell division-associated peptidoglycan amidase AmiA of Chlamydia trachomatis [PDF]
Journal of BacteriologyChlamydia is an obligate intracellular bacterium that differentiates between infectious, non-dividing EBs and non-infectious, dividing RBs. Pathogenic Chlamydia species are unusual in lacking a peptidoglycan sacculus, yet they do synthesize a transient ...
Julia Dannenberg +10 more
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Imbalance of peptidoglycan biosynthesis alters the cell surface charge of Listeria monocytogenes
The Cell Surface, 2022 The bacterial cell wall is composed of a thick layer of peptidoglycan and cell wall polymers, which are either embedded in the membrane or linked to the peptidoglycan backbone and referred to as lipoteichoic acid (LTA) and wall teichoic acid (WTA ...
Lisa Maria Schulz +4 more
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Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway. [PDF]
PLoS ONE, 2008 We hypothesized that the peptidoglycan component of B. anthracis may play a critical role in morbidity and mortality associated with inhalation anthrax. To explore this issue, we purified the peptidoglycan component of the bacterial cell wall and studied
Marybeth Langer +8 more
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Microbiology Spectrum, 2022 The cell wall peptidoglycan of bacteria is essential for their survival and shape development. The penicillin-binding proteins (PBPs) are responsible for the terminal stage of peptidoglycan assembly.
Xing Chen +8 more
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Frontiers in Immunology, 2022 The resistance of Lactobacillus plantarum to vancomycin depends on its peptidoglycan composition. Vancomycin has poor binding affinity with peptidoglycan precursors ending in D-alanyl-D-lactate (D-Ala-D-Lac) but binds strongly to peptidoglycan precursors
Xin Song +5 more
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Frontiers in Microbiology, 2023 Peptidoglycan, found within the cell wall of bacteria, is a structure critical for maintaining cell morphology and providing a protective barrier in diverse environments. Peptidoglycan is a remarkably dynamic structure that is constantly remodeled during
Beth A. Bachert, Joel A. Bozue
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eLife, 2022 The peptidoglycan cell wall is a predominant structure of bacteria, determining cell shape and supporting survival in diverse conditions. Peptidoglycan is dynamic and requires regulated synthesis of new material, remodeling, and turnover – or autolysis –
Anna Isabell Weaver +7 more
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