Results 231 to 240 of about 762,581 (360)

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

open access: yesAdvanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang   +7 more
wiley   +1 more source

Cooperativity in <i>Escherichia coli</i> L-Threonine Dehydrogenase and Its Inhibition by an Antibacterial <i>N</i>-Pyridylpyrazolone Derivative. [PDF]

open access: yesInt J Mol Sci
Obaha A   +7 more
europepmc   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

open access: yesAdvanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son   +2 more
wiley   +1 more source

Increasing pinosylvin production in Escherichia coli by reducing the expression level of the gene fabI -encoded enoyl-acyl carrier protein reductase

open access: gold, 2018
Caheri Prisciluis Salas-Navarrete   +7 more
openalex   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

open access: yesAdvanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li   +9 more
wiley   +1 more source

Toward Nanodisc Tailoring for SANS Study of Membrane Proteins. [PDF]

open access: yesBioengineering (Basel)
Batchu KC, Tully MD, Martel A.
europepmc   +1 more source

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