Results 71 to 80 of about 27,958 (218)

Functional analysis of biological matter across dimensions by atomic force microscopy (AFM): from tissues to molecules and, ultimately, atoms [PDF]

open access: yes, 2004
For a detailed understanding of biological tissues and proteins and their dynamical processes the 3D structures of the components involved must be known.
Stolz, Martin
core   +1 more source

Quantitative analysis of chloroplast protein targeting [PDF]

open access: yes
This thesis presents the first use of the Partition of Unity Method in quantifying the spatio-temporal dynamics of a fluorescent protein targeted to the chloroplast twin-arginine translocation pathway. The fluorescence loss in photobleaching technique
Li, Michael Kok Keng
core  

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

open access: yesBMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim   +5 more
wiley   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

Understanding the "rules of engagement" for membrane protein folding : chemical biology and computational approaches for determination of structure and dynamics [PDF]

open access: yes
Approximately one third of genes in the human genome (1) encode transmembrane (TM) proteins and form more than half of all drug targets (2). However, our understanding of how these proteins fold into their functional form, as well as how they may misfold
Nash, Anthony (Researcher in chemistry)
core  

Studies on the Nutritional, Functional, Textural, and Sensory Characteristics of Finger and Barnyard Millet‐Incorporated Nuggets

open access: yesFood Chemistry International, EarlyView.
The graphic illustrates the development of nuggets traditionally known as “wari” prepared with whole green grams and composite flour barnyard millet var. (PRJ‐1) and finger millet var. (VL‐M‐380) in a 1:1 ratio. The addition of millet significantly improved the nutritional value of nuggets, providing higher levels of protein, carbohydrates, fiber ...
Payal Chauhan, Mahesh Gupta
wiley   +1 more source

Parental Exposure to Nanoplastics and Graphene Oxide Induces Transgenerational Toxicity in Caenorhabditis elegans

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Environmental pollution by emerging contaminants such as nanoplastics (NPs) and graphene oxide (GO) represents a growing threat to global health and ecosystems. This study investigated the effects of parental exposure, both isolated and combined, to 100 μg/L NPs (polystyrene, spherical, 100 nm) and 100 mg/L GO, using Caenorhabditis elegans as ...
Gabriela Corrêa Soares   +6 more
wiley   +1 more source

Physicochemical properties, fermentative profile, microbiological quality, and pathogen contamination of baled silage during long‐term storage

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Baled silage is expanding in Mediterranean regions due to climate change and demand for high‐quality forage; therefore, evaluating the effects of long‐term storage on microbiological and fermentative quality is essential. RESULTS In this study, 115 baled silages were sampled from different farms at 30, 60, 90, 180, and 270 days ...
Lidia Nieddu   +6 more
wiley   +1 more source

On the Assembly of Actin Polymerization‐Powered Motors

open access: yesMacromolecular Rapid Communications, EarlyView.
Actin polymerization‐powered motors have the highest speed when the actin recruiting‐polymerizing proteins are immobilized in polymer brushes on their surface. These motors orbit around larger tracer particles at pH above the isoelectric point of ActA but dock onto the tracer particles’ surface at lower pH. ABSTRACT Nano‐ and micromotors are a class of
Miguel A. Ramos Docampo   +2 more
wiley   +1 more source

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