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Biological and molecular characterisation of in vitro selected miltefosine-resistant Leishmania amazonensis lines [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceMiltefosine (MTF) is currently the only available oral treatment for leishmaniasis. However, increasing reports of therapeutic failure have raised concerns about emerging resistance.
Laura Fernanda Neira +4 more
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Protocol for generating human cerebral organoids from two-dimensional cultures of pluripotent stem cells bypassing embryoid body aggregation [PDF]
STAR ProtocolsSummary: Human cerebral organoids (hCOs) provide an excellent model for the study of human brain development and disease. Here, we present a protocol to obtain hCOs directly from two-dimensional (2D) pluripotent stem cell (PSC) cultures, avoiding cell ...
Rosa González-Sastre +8 more
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Age as a Predictor of Overall Survival in Colorectal Cancer [PDF]
DiagnosticsBackground: The diagnosis of colorectal cancer (CRC) at early ages has become a challenging trend for oncology due to high rates of mortality worldwide. The correlation of clinical features with young-age prognosis in CRC remains unclear.
Berenice Carbajal-López +9 more
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Hexágono Pedagógico, 2022 El propósito del estudio fue des encubrir las colonialidades del ser y del saber subyacentes en la práctica educativas desarrolladas en el momento de la casa-escuela del devenir histórico de la educación en Matitas, La Guajira, las cuales perpetúan ...
Danis Eduardo Ruíz Toro +1 more
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Human cerebral organoids: cellular composition and subcellular morphological features [PDF]
Frontiers in Cellular NeuroscienceIntroductionHuman cerebral organoids (hCOs) derived from pluripotent stem cells are very promising for the study of neurodevelopment and the investigation of the healthy or diseased brain.
Patricia Mateos-Martínez +12 more
doaj +2 more sources
Efficient generation of human cerebral organoids directly from adherent cultures of pluripotent stem cells [PDF]
Journal of Tissue EngineeringHuman cerebral organoids (hCOs) offer the possibility of deepening the knowledge of human brain development, as well as the pathologies that affect it.
Rosa González-Sastre +6 more
doaj +2 more sources
Life Satisfaction and Family Communication as Protective Factors in Problematic Internet Use in University Students [PDF]
SAGE Open NursingIntroduction Problematic Internet use (PIU) is considered a serious condition and a potential factor for various physical and psychological health problems, with higher prevalence rates in the young adult population, a situation aggravated by mandatory ...
Walter Capa-Luque +7 more
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Cuadernos de investigación UNED, 2021 Introduction: The implementation of wastewater treatment systems such as constructed wetlands has a growing interest in the last decade due to its low cost and high effectiveness in treating industrial and residential wastewater.
Junior Pastor Pérez-Molina +11 more
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Cuadernos de investigación UNED, 2023 Introduction: The spread of antimicrobial resistance in natural environments continues to be reported throughout the world; nevertheless, there is no study about phytotelms (water in the natural cavities of plants) in the deep understory of tropical ...
Stephanny Sánchez-Vargas +3 more
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Plants, 2023 Anthropogenic disturbance of tropical humid forests leads to habitat loss, biodiversity decline, landscape fragmentation, altered nutrient cycling and carbon sequestration, soil erosion, pest/pathogen outbreaks, among others.
José Luis Pablo-Rodríguez +9 more
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