Results 31 to 40 of about 5,972 (165)

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

The 1976 Guatemala Earthquake: ESI Scale and Probabilistic/Deterministic Seismic Hazard Analysis Approaches

, 2019
A hazard assessment of the 1976 Guatemala earthquake (M = 7.5) was conducted to achieve a better definition of the seismic hazard. The assessment was based on the environmental effects that had effectively contributed to the high destructive impact of ...
Sacchi, Marco, Porfido, Sabina, Marco Sacchi, Sabina Porfido, Spiga, Efisio, Efisio Spiga, Mauro Caccavale, Caccavale, Mauro   +7 more
core   +1 more source

Rapid and comprehensive evaluation of (poly)phenolic compounds in pomegranate (punica granatum L.) juice by UHPLC-MSn [PDF]

, 2012
The comprehensive identification of phenolic compounds in food and beverages is a crucial starting point for assessing their biological, nutritional, and technological properties.
Bruni, Renato, Luca Calani, Galaverna, Gianni, Cristina García-Viguera, Mena, P., Renato Bruni, Dall'Asta, C., Calani, Luca, Crozier A, DEL RIO, Daniele, Pedro Mena, Alan Crozier, Bruni, R., MENA PARRENO, Pedro Miguel, Garcia Viguera C, García-Viguera, C., Dall'Asta, Chiara, Chiara Dall'Asta, Mena, Pedro, Gianni Galaverna, Crozier, A., Daniele Del Rio, Chiara Dall\u27Asta, Calani, L., García-Viguera, Cristina, Rio, Daniele del, Del Rio, D., Galaverna, G., Crozier, Alan   +28 more
core   +1 more source

Deciphering unusually large modulations in two related organic hydroxy channel structures

Acta Crystallographica Section B, EarlyView.
Two related organic hydroxy‐channel compounds are shown to have unusually large structural modulations.The incommensurately modulated structures of two related organic hydroxy‐channel compounds [(R)‐1‐(1,3‐dihydroxypropan‐2‐yl)‐3‐(octan‐2‐yl)urea, 1; 1‐(1,3‐dihydroxypropan‐2‐yl)‐3‐octylurea, 2] have been determined and compared to the structure of a ...
Arie van der Lee, Ioan Stroia, Li-Bo Huang, Erol Licsandru, Istvan Kocsis, Mihail Deleanu, Christian Hübschle, Mihail Barboiu, Olivier Pérez   +8 more
wiley   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Coloniality of Skill Codification: A Decolonial Feminist Analysis of “Ideal Workers” in the “Future of Work” Policy Discourses

Gender, Work &Organization, EarlyView.
ABSTRACT Over the last decade, policy actors have produced a surge of “future of work” reports that reimagine workers through the dual logics of digitalization and human capital. Drawing on 25 policy documents (WEF, World Bank, OECD, EU, and major consultancies) and combining Bacchi and Goodwin's WPR approach with decolonial feminist theory, this paper
Muneeb Ul Lateef Banday
wiley   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

Aplicación de la escala ESI-2007 para el análisis de efectos medio ambientales e intensidades en los sismos: Tumaco (Mw = 8.1, 1979) y Armenia (Mw = 6.1, 1999), Colombia [PDF]

, 2018
A partir de los sismos del 25 de enero de 1999, sismo de Armenia (SA); y el del 12 de diciembre de 1979, sismo de Tumaco (ST), se realiza el análisis de efectos ambientales, estimación de intensidad, cuantificación de áreas de afectación y comparación de
Tovar Vergara, Freddy
core