Results 21 to 30 of about 1,736,474 (279)

Phase 1 clinical trial to assess safety and efficacy of NY-ESO-1-specific TCR T cells in HLA-A∗02:01 patients with advanced soft tissue sarcoma

Cell Reports Medicine, 2023
Summary New York esophageal squamous cell carcinoma-1 (NY-ESO-1)-specific T cell receptor (TCR) T cell therapy is effective in tumors with NY-ESO-1 expression, but a safe and effective TCR-T cell therapeutic protocol remains to be improved.
Q. Pan, Desheng Weng, Jiayong Liu, Zhaosheng Han, Yusheng Ou, Bu-Shu Xu, R. Peng, Y. Que, X. Wen, Jing Yang, Shi Zhong, L. Zeng, Aiyuan Chen, Haiping Gong, Yanmei Lin, Jiewen Chen, Ke Ma, J. Lau, Yi Li, Z. Fan, Xing Zhang   +20 more
semanticscholar   +1 more source

Current advances in cancer vaccines targeting NY-ESO-1 for solid cancer treatment

Frontiers in Immunology, 2023
New York-esophageal cancer 1 (NY-ESO-1) belongs to the cancer testis antigen (CTA) family, and has been identified as one of the most immunogenic tumor-associated antigens (TAAs) among the family members.
Hong Zhou, Yipeng Ma, Fenglan Liu, Bin Li, Dongjuan Qiao, Peigen Ren, Mingjun Wang   +6 more
semanticscholar   +1 more source

European Stroke Organisation (ESO) guidelines on management of unruptured intracranial aneurysms

European Stroke Journal, 2022
Unruptured intracranial aneurysms (UIA) occur in around 3% of the population. Important management questions concern if and how to perform preventive UIA occlusion; if, how and when to perform follow up imaging and non-interventional means to reduce the ...
N. Etminan, D. A. de Sousa, C. Tiseo, R. Bourcier, H. Desal, A. Lindgren, T. Koivisto, D. Netuka, S. Peschillo, S. Lémeret, A. Lal, M. Vergouwen, G. Rinkel   +12 more
semanticscholar   +1 more source

European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage

European Stroke Journal, 2021
The optimal blood pressure (BP) management in acute ischaemic stroke (AIS) and acute intracerebral haemorrhage (ICH) remains controversial. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist physicians in
E. Sandset, C. Anderson, P. Bath, H. Christensen, U. Fischer, D. Gąsecki, A. Lal, L. Manning, S. Sacco, T. Steiner, G. Tsivgoulis   +10 more
semanticscholar   +1 more source

NY-ESO-1-specific redirected T cells with endogenous TCR knockdown mediate tumor response and cytokine release syndrome

Journal for ImmunoTherapy of Cancer, 2022
Background Because of the shortage of ideal cell surface antigens, the development of T-cell receptor (TCR)-engineered T cells (TCR-T) that target intracellular antigens such as NY-ESO-1 is a promising approach for treating patients with solid tumors ...
M. Ishihara, S. Kitano, S. Kageyama, Y. Miyahara, N. Yamamoto, H. Kato, H. Mishima, Hiroyoshi Hattori, T. Funakoshi, T. Kojima, T. Sasada, Eiichi Sato, S. Okamoto, D. Tomura, I. Nukaya, H. Chono, J. Mineno, Muhammad Faris Bin Mohd Kairi, Phuong Diem Hoang Nguyen, Y. Simoni, A. Nardin, E. Newell, M. Fehlings, H. Ikeda, Takashi Watanabe, H. Shiku   +25 more
semanticscholar   +1 more source

Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy

Journal for ImmunoTherapy of Cancer, 2022
Background The current therapeutic antibodies and chimeric antigen receptor (CAR) T cells are capable of recognizing surface antigens, but not of intracellular proteins, thus limiting the target coverage for drug development.
Xin Liu, Yixiang Xu, Wei Xiong, Bingnan Yin, Yuqian Huang, Junjun Chu, Changsheng Xing, Chen Qian, Yang Du, Tianhao Duan, Helen Y Wang, Ningyan Zhang, John S. Yu, Z. An, Rongfu Wang   +14 more
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ESO-ESMO 4rd International Consensus Guidelines for Breast Cancer in Young Women (BCY4).

Annals of Oncology, 2020
The 4th International Consensus Conference for Breast Cancer in Young Women (BCY4) took place in October 2018, in Lugano, Switzerland, organized by the European School of Oncology (ESO) and the European Society of Medical Oncology (ESMO).
S. Paluch-Shimon, Fatima Cardoso, A. Partridge, OMalkahi Abulkhair, H. Azim, G. Bianchi-Micheli, M. Cardoso, G. Curigliano, K. Gelmon, N. Harbeck, J. Merschdorf, P. Poortmans, G. Pruneri, E. Senkus, T. Španić, V. Stearns, Y. Wengström, F. Peccatori, O. Pagani   +18 more
semanticscholar   +1 more source

Second-Order ESO-Based Current Sensor Fault-Tolerant Strategy for Sensorless Control of PMSM With B-Phase Current

IEEE/ASME transactions on mechatronics, 2022
Usually, two-phase current sensors are required to realize sensorless control of permanent magnet synchronous motor (PMSM). However, once the phase current sensor fails, the whole system will not work. In this article, a novel second-order extended state
Zhaohua Liu, Jie Nie, Hua‐Liang Wei, Lei Chen, Faquan Wu, Mingyang Lv   +5 more
semanticscholar   +1 more source

ASASSN-14ko is a Periodic Nuclear Transient in ESO 253-G003 [PDF]

Astrophysical Journal, 2020
We present the discovery that ASASSN-14ko is a periodically flaring active galactic nucleus at the center of the galaxy ESO 253-G003. At the time of its discovery by the All-Sky Automated Survey for Supernovae (ASAS-SN), it was classified as a supernova ...
A. Payne, B. Shappee, J. Hinkle, P. Vallely, C. Kochanek, T. Holoien, K. Auchettl, K. Stanek, T. Thompson, J. Neustadt, M. Tucker, J. Armstrong, J. Brimacombe, P. Cacella, R. Cornect, L. Denneau, M. Fausnaugh, H. Flewelling, D. Grupe, A. Heinze, L. Lopez, B. Monard, J. Prieto, A. Schneider, S. Sheppard, J. Tonry, H. Weiland   +26 more
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Impact of satellite constellations on astronomical observations with ESO telescopes in the visible and infrared domains [PDF]

Astronomy & Astrophysics, 2020
The effect of satellite mega-constellations on astronomical observations in the visible, near-infrared, and thermal infrared domains is estimated using a simple methodology, which is applied to ESO telescopes and instruments as examples (radio and (sub ...
O. Hainaut, A. Williams
semanticscholar   +1 more source