Results 51 to 60 of about 115,341 (318)
Metabolomics study of esophageal adenocarcinoma [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2011 The objective of this study was to detect and evaluate reliable metabolite markers for screening and monitoring treatment of patients with esophageal adenocarcinoma (EAC) by studying metabolomics. The sensitivity and specificity of the study were evaluated not only for EAC but also for Barrett esophagus and high-grade dysplasia, which are widely ...
Zhang, Jian +6 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Case Reports in Otolaryngology, 2018 Distant metastasis to the jaws, including the maxilla or mandible, is very rare. Although the mandible is the preferred sight of these rare metastases, it is extremely rare for oral cavity malignancies to present as pathological mandibular fractures ...
Daniel C. O’Brien +3 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
BMC Cancer, 2021 Background For patients with esophageal adenocarcinoma or cancer of the gastroesophageal junction, radical esophagectomy with 2-field lymphadenectomy is the cornerstone of the multimodality treatment with curative intent.
E. Tagkalos +13 more
doaj +1 more source
Opportunities for Preventing Esophageal Adenocarcinoma [PDF]
Cancer Prevention Research, 2016 Abstract Esophageal adenocarcinoma (EAC) is rapidly increasing in incidence in many Western societies, requires demanding treatment, and is associated with a poor prognosis, therefore preventive measures are highly warranted. To assess the opportunities for prevention, we reviewed the available literature and identified seven main ...
Maret-Ouda, John +2 more
openaire +3 more sources
Advanced Science, EarlyView.Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian +11 more
wiley +1 more source
Signatures within the esophageal microbiome are associated with host genetics, age, and disease
Microbiome, 2018 Background The esophageal microbiome has been proposed to be involved in a range of diseases including the esophageal adenocarcinoma cascade; however, little is currently known about its function and relationship to the host.
Nandan P. Deshpande +4 more
doaj +1 more source
Surgical approaches to adenocarcinoma of the gastroesophageal junction: the Siewert II conundrum. [PDF]
, 2017 BACKGROUND: The Siewert classification system for gastroesophageal junction adenocarcinoma has provided morphological and topographical information to help guide surgical decision-making.
Berger, Adam C. +4 more
core +1 more source
The Epidemiology of Esophageal Adenocarcinoma [PDF]
Gastroenterology, 2018 The incidence of esophageal adenocarcinoma (EAC) has increased in many Western countries and is higher in men than women. Some risk factors for EAC have been identified-mainly gastroesophageal reflux disease, Barrett's esophagus, obesity, and tobacco smoking.
Helen G. Coleman +2 more
openaire +5 more sources