Results 41 to 50 of about 295,792 (196)

Characterization of Desmoglein 3 (DSG3) as a Sensitive and Specific Marker for Esophageal Squamous Cell Carcinoma

open access: yesGastroenterology Research and Practice, 2022
Although P40 and P63 are both sensitive and specific for routine esophageal squamous cell carcinoma (SCC) diagnosis, we recently showed that P40 and P63 immunoreactivities were significantly lower in well-differentiated SCC than those in higher grade ...
Zhikai Chi   +5 more
doaj   +1 more source

OPCML is hypermethylated in a subset of patients with metaplastic changes in their esophagus

open access: yesBiomarker Research, 2018
OPCML hypermethylation is considered a promising cancer biomarker. We examined methylation levels in the first exon of OPCML in two patient cohorts within the esophageal adenocarcinoma and gastric adenocarcinoma cascades and in a range of cell-lines ...
Natalia Castaño-Rodríguez   +10 more
doaj   +1 more source

Circulatory Tumor Cells in Esophageal Adenocarcinoma

open access: yes, 2018
While circulating tumor cells (CTCs) within peripheral blood of cancer patients are no new phenomenon in many carcinomas, there is a lack of information on the biological and clinical implications of CTCs in esophageal adenocarcinomas.
Lam, AK   +5 more
core   +1 more source

Case Report and Literature Review of a Pathologic Mandibular Fracture from Metastatic Esophageal Adenocarcinoma

open access: yesCase Reports in Otolaryngology, 2018
Distant metastasis to the jaws, including the maxilla or mandible, is very rare. Although the mandible is the preferred sight of these rare metastases, it is extremely rare for oral cavity malignancies to present as pathological mandibular fractures ...
Daniel C. O’Brien   +3 more
doaj   +1 more source

Application of Tissue Microarray in Esophageal Adenocarcinoma

open access: yes, 2018
Tissue microarray technology could allow immunohistochemical staining or in situ hybridization on hundreds of different tissue samples simultaneously. It allows faster analysis and considerably reducing costs incurred in staining.
Lam, AK   +5 more
core   +1 more source

Identification of Cancer Stem Cells in Esophageal Adenocarcinoma

open access: yes, 2018
Cancer stem cells (CSCs) are a subpopulation of cancer cells that have the ability to self-renew and to generate differentiated cells of various lineages.
Islam, F   +8 more
core   +1 more source

Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy versus minimally invasive esophagectomy for resectable esophageal adenocarcinoma, a randomized controlled trial (ROBOT-2 trial)

open access: yesBMC Cancer, 2021
Background For patients with esophageal adenocarcinoma or cancer of the gastroesophageal junction, radical esophagectomy with 2-field lymphadenectomy is the cornerstone of the multimodality treatment with curative intent.
E. Tagkalos   +13 more
doaj   +1 more source

Nonsurgical Management of Esophageal Adenocarcinoma

open access: yesClinical Colorectal Cancer, 2011
The benefit of induction chemotherapy (IC) before chemoradiotherapy (CRT) for inoperable esophageal adenocarcinoma has not been established. To clarify toxicities and outcomes of combined modality treatment, we performed a retrospective review.Sixty-eight consecutive patients were identified. Fifty-one patients had CRT, 17 had radiotherapy (RT).
Gujral, D   +6 more
openaire   +3 more sources

Epigenetics in the Pathogenesis of Esophageal Adenocarcinoma [PDF]

open access: yesClinical and Translational Science, 2014
AbstractEpigenetic influences, such as DNA methylation, histone acetylation, and up‐regulation/down‐regulation of genes by microRNAs, change the genetic makeup of an individual without affecting DNA base‐pair sequences. Indeed, epigenetic changes play an integral role in the progression from normal esophageal mucosa to Barrett's esophagus to esophageal
Aparna, Kailasam   +2 more
openaire   +2 more sources

Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice

open access: yesBMC Gastroenterology, 2009
Background Esophago-gastroduodenal anastomosis with rats mimics the development of human Barrett's esophagus and esophageal adenocarcinoma by introducing mixed reflux of gastric and duodenal contents into the esophagus. However, use of this rat model for
Chen Xiaoxin   +3 more
doaj   +1 more source

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