Results 21 to 30 of about 295,792 (196)
BMC Gastroenterology, 2012 Background High expression of Bmi-1, a key regulatory component of the polycomb repressive complex-1, has been associated with many solid and hematologic malignancies including esophageal squamous cell carcinoma.
Choy Bonnie +9 more
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Translational Oncology, 2018 BACKGROUND: Barrett's esophagus metaplasia is the key precursor lesion of esophageal adenocarcinoma. The aim of this study was to find a subset of markers that may allow the identification of patients at risk for esophageal adenocarcinoma, and to ...
Yiyang Dai +6 more
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From Reflux Esophagitis to Esophageal Adenocarcinoma [PDF]
Digestive Diseases, 2016 Reflux esophagitis causes Barrett's metaplasia, an abnormal esophageal mucosa predisposed to adenocarcinoma. Medical therapy for reflux esophagitis focuses on decreasing gastric acid production with proton pump inhibitors. We have reported that reflux esophagitis in a rat model develops from a cytokine-mediated inflammatory injury, not from a caustic ...
openaire +2 more sources
Salvage endoscopic resection in patients with esophageal adenocarcinoma after chemoradiotherapy
Endoscopy International Open, 2018 Background and study aims For early esophageal adenocarcinoma, endoscopic resection is an accepted curative treatment with an excellent long-term prognosis.
Irma C. Noordzij +6 more
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Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]
, 2005 Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Jauch, Karl-Walter +2 more
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Вестник хирургии имени И.И. Грекова, 2018 The article presents an analysis of results of 24 384 endoscopic examinations of the upper gastrointestinal tract in population of the Leningrad oblast with symptoms of gastric dyspepsia during the period from 2007 to 2011.
D. I. Vasilevsky +9 more
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Metabolomics study of esophageal adenocarcinoma [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2011 The objective of this study was to detect and evaluate reliable metabolite markers for screening and monitoring treatment of patients with esophageal adenocarcinoma (EAC) by studying metabolomics. The sensitivity and specificity of the study were evaluated not only for EAC but also for Barrett esophagus and high-grade dysplasia, which are widely ...
Zhang, Jian +6 more
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The Turkish Journal of Gastroenterology, 2014 Background/Aims: Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is an oncofetal protein with vital function during human embryogenesis in terms of cellular growth and migration.
Behrang Kazeminezhad +4 more
doaj +1 more source
Insights Into the Pathophysiology of Esophageal Adenocarcinoma [PDF]
Gastroenterology, 2018 Although researchers have identified genetic alterations that contribute to development of esophageal adenocarcinoma, we know little about features of patients or environmental factors that mediate progression of chronic acid biliary reflux to Barrett's esophagus and cancer.
Michael Quante +2 more
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Targeted Single Gene Mutation in Esophageal Adenocarcinoma
, 2018 Esophageal adenocarcinoma is heterogeneous and studies have reviewed many important mutations that contribute to the pathogenesis of the cancer. These discoveries have helped paved the way into identifying new gene markers or gene targets to develop ...
Lam, AK +7 more
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