Results 51 to 60 of about 295,792 (196)

Signatures within the esophageal microbiome are associated with host genetics, age, and disease

Microbiome, 2018
Background The esophageal microbiome has been proposed to be involved in a range of diseases including the esophageal adenocarcinoma cascade; however, little is currently known about its function and relationship to the host.
Nandan P. Deshpande, Stephen M. Riordan, Natalia Castaño-Rodríguez, Marc R. Wilkins, Nadeem O. Kaakoush   +4 more
doaj   +1 more source

Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells

Technology in Cancer Research & Treatment, 2020
Cancer stem cells, a special subgroup of cancer cells, have self-renewal capabilities and multidirectional potential, which may be reprogrammed from the dedifferentiation of cancer cells, contributing to the failure of clinical treatments.
Mei Chen BSc, AXiaojun Ye MSc, Jingxi Wei BSc, Ruihua Wang MD, Karen Poon PhD   +4 more
doaj   +1 more source

The Male Predominance in Esophageal Adenocarcinoma [PDF]

Clinical Gastroenterology and Hepatology, 2016
The incidence of esophageal adenocarcinoma (EAC) has increased rapidly during the past 4 decades in many Western populations, including North America and Europe. The established etiological factors for EAC include gastroesophageal reflux and obesity, Helicobacter pylori infection, tobacco smoking, and consumption of fruit and vegetables.
Shao-Hua Xie, Jesper Lagergren
openaire   +4 more sources

Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]

, 2008
<b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Didevar, R., Derakhshan, M.H., Watabe, H., Yazdanbod, A., Rakhshani, N., Zolfeghari, A., McColl, K.E.L., Zolfeghari, A.A., Fyfe, V., Sotoudeh, M., Malekzadeh, R., Kazemi, A.   +11 more
core   +1 more source

GWAS meta-analysis of 16 790 patients with Barrett\u2019s oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level

, 2022
: Objective Oesophageal cancer (EC) is the sixth leading cause of cancer-related deaths. Oesophageal adenocarcinoma (EA), with Barrett\u2019s oesophagus (BE) as a precursor lesion, is the most prevalent EC subtype in the Western world. This study aims to
Thieme, Rene, Maj, Carlo, Gehlen, Jan, Yogesh Vashist, Ines Gockel, M\ufcller, Michaela, H\uf6lscher, Arnulf H., Weism\ufcller, Josef, Rösch, Thomas, May, Sandra, Gerges, Christian, Messmann, Helmut, Arne Dietrich, B\uf6hmer, Anne C., Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), Ebigbo, Alanna, Daniel Reim, Christiane J Bruns, Ong, Jue-Sheng, Jue-Sheng Ong, David Ellinghaus, Lang, Hauke, Dani Dakkak, Laura Chegwidden, Vaughan, Thomas L., Julian Reingruber, Sandra May, Weismüller, Josef, Franke, Andre, Vieth, Michael, Ellinghaus, David, Thomas L Vaughan, Görg, Siegfried, Ian Tomlinson, Dominik Heider, Hohaus, Michael, Jennis Kandler, null null, Hölscher, Arnulf H, Speller, Jan, Udo Benner, Whiteman, David C., Hoffmeister, Albrecht, Prenen, Hans, Alanna Ebigbo, Lordick, Florian, Chegwidden, Laura, Vaughan, Thomas L, Bruns, Christiane J., Dommermuth, Jens, Schmidt, Carsten, Schr\uf6der, Julia, Florian Lordick, Borisov, Oleg, G\uf6rg, Siegfried, Fuchs, Claudia, Kandler, Jennis, Andreas Mayr, David C Whiteman, Andrea May, Nöthen, Markus M, Dakkak, Dani, Rene Thieme, Janusz Jankowski, Stuart MacGregor, Matthew F Buas, Müller, Michaela, Tomlinson, Ian, Jan Gehlen, N\uf6then, Markus M., Bruns, Christiane J, Michael Vieth, Schumacher, Brigitte, Lothar Veits, Puya Gharahkhani, Lyros, Orestis, Böhmer, Anne C, Michaela Müller, Helmut Messmann, Horst Neuhaus, Jankowski, Janusz, Julia Schröder, Grimminger, Peter P, Thomas Schmidt, Christian Gerges, Thrift, Aaron P., Jan Speller, Dietrich, Arne, Kreuser, Nicole, Arnulf H Hölscher, Sara Galavotti, Reim, Daniel, Wissinowski, Thaddäus T, Aaron P Thrift, Neuhaus, Horst, Gockel, Ines, Rebecca Claire Fitzgerald, Palles, Claire, Hillmer, Axel M., Orestis Lyros, Josef Weismüller, May, Andrea, Claudia Fuchs, Matthias Mehdorn, Benner, Udo, Esophageal Adenocarcinoma Genetics Consortium (EAGLE), Marino Venerito, Nicole Kreuser, Schmidt, Thomas, Grimminger, Peter P., Thaddäus T Wissinowski, Vashist, Yogesh, Whiteman, David C, Schröder, Julia, Venerito, Marino, Heider, Dominik, Wissinowski, Thadd\ue4us T., Thomas Rösch, Johannes Schumacher, Thrift, Aaron P, Oleg Borisov, Carsten Schmidt, Anne C Böhmer, Peter P Grimminger, Stocker, Gertraud, Brigitte Schumacher, Hillmer, Axel M, Jens Dommermuth, Hess, Timo, Claire Palles, Mehdorn, Matthias, R\uf6sch, Thomas, Gharahkhani, Puya, Jing Dong, Veits, Lothar, Buas, Matthew F, Timo Hess, Reingruber, Julian, Hauke Lang, Markus M Nöthen, Hakan Alakus, Michael Hohaus, Galavotti, Sara, Andre Franke, Schumacher, Johannes, Axel M Hillmer, Wellcome Trust Case Control Consortium 2 (WTCCC2), Albrecht Hoffmeister, Mayr, Andreas, Carlo Maj, Alakus, Hakan, MacGregor, Stuart, Siegfried Görg, Dong, Jing, Gertraud Stocker, Buas, Matthew F., Fitzgerald, Rebecca Claire   +156 more
core   +1 more source

Neoangiogenesis. Assessment in Esophageal Adenocarcinomas [PDF]

Indian Journal of Surgery, 2014
Esophageal cancer has always been subject of research for various studies. According to some authors, esophageal cancer represents the 10th leading cause of cancer in the world with a 5-year survival of 10 %. In terms of anatomopathological form of the esophageal neoplasia, the literature mainly describes two major pathological types: adenocarcinoma ...
Valeriu, Ardeleanu, Laurian, Francu, Costinela, Georgescu   +2 more
openaire   +2 more sources

Whole-Slide Imaging for Esophageal Adenocarcinoma

, 2018
Whole-slide imaging revolutionizes the field of pathology especially in the areas of facilitation of research, long-term storages, exchange of information, and image analysis.
Lam, AK, Melissa Leung, Lam, Alfred, Leung, M, Leung, Yuk-Ying, Alfred K. Lam   +5 more
core   +1 more source

Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]

, 2013
Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Klautke, Gunther, Galle, Peter R., Brenner, Baruch, Arnold, Dirk, Roessler, Hans-Peter, Thomaidis, Thomas, Schimanski, Carl Christoph, Schmidberger, Heinz, Rödel, Claus, Gockel, Ines, Möhler, Markus, Trarbach, Tanja, Lang, Hauke   +12 more
core   +1 more source

Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma

BMC Gastroenterology, 2011
Background The continuous exposure of esophageal epithelium to refluxate may induce ectopic expression of bile-responsive genes and contribute to the development of Barrett's esophagus (BE) and esophageal adenocarcinoma.
Kusters Johannes G, Siersema Peter D, van Dekken Herman, Pot Raymond GJ, Moons Leon MG, Capello Astrid, Menke Vivianda, van de Winkel Anouk, van der Laan Luc JW, Kuipers Ernst J   +9 more
doaj   +1 more source

Area-level attributes and esophageal adenocarcinoma in surveillance, epidemiology and end results registries. [PDF]

PLoS ONE, 2013
PURPOSE: To examine the associations between area-level socioeconomic attributes and stage of esophageal adenocarcinoma diagnoses in 16 SEER cancer registries during 2000-2007.
Armen A Ghazarian, Megan A Murphy, Maria R Khan, Brit I Saksvig, Sean F Altekruse   +4 more
doaj   +1 more source