Results 101 to 110 of about 266,260 (301)

Microarray Analysis of Radioresistance-associated Genes in Esophageal Squamous Cell Carcinoma

Zhongliu Fangzhi Yanjiu, 2019
Objective To identify the novel radioresistance-associated genes in esophageal squamous cell carcinoma and build a foundation for the individualized radiotherapy.
ZHU Qingshan, LI Junkuo, LIU Weipeng, MA Tingwei, DAI Ningtao, FENG Lianjie, WEI Tao, ZHOU Fuyou   +7 more
doaj   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Esophageal Cancer Staging

The Korean Journal of Thoracic and Cardiovascular Surgery, 2015
Accurate staging of esophageal cancer is very important to achieving optimal treatment outcomes. The AJCC (American Joint Committee on Cancer) first published TNM esophageal cancer staging recommendations in the first edition of their staging manual in 1977. Thereafter, the staging of esophageal cancer was changed many times over the years.
openaire   +2 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Prospective Study on Tooth Loss and Risk of Esophageal Cancer Among Residents of A Natural Village in Wenfeng District, Anyang City, Henan Province

Zhongliu Fangzhi Yanjiu
ObjectiveTo investigate the relationship between tooth loss and the occurrence of esophageal cancer in a natural village in Wenfeng District, Anyang City, Henan Province.
Jingjing WANG, Ruihua XU, Yanfang ZHANG, Xueke ZHAO, Qiang ZHANG, Xin SONG, Mengxia WEI, Junfang GUO, Xuena HAN, Yaru FU, Bei LI, Junqing LIU, Lingling LEI, Min LIU, Qide BAO, Lidong WANG   +15 more
doaj   +1 more source

Niclosamide, an antihelmintic drug, enhances efficacy of PD-1/PD-L1 immune checkpoint blockade in non-small cell lung cancer

Journal for ImmunoTherapy of Cancer, 2019
Background PD-1/PD-L1 blockade has received approval for clinical application due to its encouraging benefit with improving prognosis in selected populations. Unfortunately, the response to immunotherapy for many patients remains unsatisfactory.
Fan Luo, Min Luo, Qi-Xiang Rong, Hong Zhang, Zhen Chen, Fang Wang, Hong-Yun Zhao, Li-Wu Fu   +7 more
doaj   +1 more source

Authentication of newly established human esophageal squamous cell carcinoma cell line (YM-1) using short tandem repeat (STR) profiling method [PDF]

, 2016
Cross-contamination during or early after establishment of a new cell line could result in the worldwide spread of a misidentified cell line. Therefore, newly established cell lines need to be authenticated by a reference standard method.
Ayyoob, K., Jahanbakhsh, A., Masoud, K., Vahideh, K.   +3 more
core  

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

Advanced Science, EarlyView.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu, Jiajia Zhuo, Xiaoquan Hong, Shihao Rao, Yafang Ye, Dandan Kang, Huifang Peng, Huiqin Zhuo   +7 more
wiley   +1 more source

Relationship Between Gastroesophageal Reflux Disease-Related Symptoms and Clinicopathologic Characteristics and Long-Term Survival of Patients with Esophageal Adenocarcinoma in China

Zhongliu Fangzhi Yanjiu
ObjectiveTo investigatethe relationship between gastroesophageal reflux disease (GERD) symptoms and clinicopathological characteristics, p53 expression, and survival of Chinese patients with esophageal adenocarcinoma. MethodsA total of 3882 patients with
Kan ZHONG, Xin SONG, Ran WANG, Mengxia WEI, Xueke ZHAO, Lei MA, Quanxiao XU, Jianwei KU, Lingling LEI, Wenli HAN, Ruihua XU, Jin HUANG, Zongmin FAN, Xuena HAN, Wei GUO, Xianzeng WANG, Fuqiang QIN, Aili LI, Hong LUO, Bei LI, Lidong WANG   +20 more
doaj   +1 more source

Dacomitinib potentiates the efficacy of conventional chemotherapeutic agents via inhibiting the drug efflux function of ABCG2 in vitro and in vivo

Journal of Experimental & Clinical Cancer Research, 2018
Background ATP-binding cassette subfamily G member 2 (ABCG2), a member of the ABC transporter superfamily proteins, mediates multidrug resistance (MDR) by transporting substrate anticancer drugs out of cancer cells and decreasing their intracellular ...
Xiaoran Guo, Kenneth K. W. To, Zhen Chen, Xiaokun Wang, Jianye Zhang, Min Luo, Fang Wang, Shirong Yan, Liwu Fu   +8 more
doaj   +1 more source