Results 191 to 200 of about 4,804,665 (363)

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio, Huijie Yuan, Leandro Raul Soria, Sara Basse Hansen, Iolanda Boffa, Paola Arena, Benedetta Attianese, Maureen. O'Sullivan, Noelle Cullinan, Lewis Pang, Daan Marinus Ferdinand van Aalten, Nicola Brunetti‐Pierri, Sally Ann Lynch   +12 more
wiley   +1 more source

Bibliometric analysis of immunotherapy for esophageal cancer: 2004-2024. [PDF]

Front Oncol
Hua Y, Liu Y, Liu Y, Tian X, Zhang X, You J, Yin F.   +6 more
europepmc   +1 more source

Spontaneous Ventilation and Epidural Anesthesia in a Patient with a Large Tracheoesophageal Fistula and Esophageal Cancer Undergoing Colon interposition [PDF]

, 1993
G Pittoni, G. Davià, F Toffoletto, G. P. Giron   +3 more
openalex   +1 more source

The Vietnamese swine as a translational model of invasive ductal carcinoma of the breast

Animal Models and Experimental Medicine, EarlyView.
The flow diagram outlines the chemical induction of breast tumors through a single intraperitoneal dose of MNU. Tumor development was assessed using ultrasound and clinical examination. After 14 weeks, mammary tissue was collected and histologically analyzed to evaluate structural similarities between sows and humans, the carcinogenic potential of MNU,
Claudia Elizabeth Vera‐Tizatl, Arturo Vera‐Hernández, Lorenzo Leija‐Salas, Marco Antonio Vega‐López, María del Carmen Ramírez‐Estudillo, German Isauro Garrido Fariña, Adriana Leticia Vera‐Tizatl   +6 more
wiley   +1 more source

Psoriasis caused by camrelizumab in a patient with esophageal cancer: a case report. [PDF]

Front Med (Lausanne)
Duan Y, Chen J, Zhong D, Xiong X.
europepmc   +1 more source

Lymph flow and lymph node metastasis of the thoracic esophageal cancer.

, 1987
Masamichi Baba, Kazunao KUROSIMA, Gen Tanabe, Shoji Natsugoe, Heiji Yoshinaka, Yuzo KAWASAKI, Atushi MIRE, Hiroshi MURE, Toshitaka Fukumoto, Masahiro MATUNO, Takashi Aikou, T Kajisa, Hisaaki Shimazu, Mitsumasa Nishi   +13 more
openalex   +2 more sources

Identification of a Proteolysis‐Targeting‐Chimera that Addresses Activated Checkpoint Kinase‐1 Reveals its Non‐Catalytic Functions in Tumor Cells

Angewandte Chemie International Edition, EarlyView.
In cancer cells, the induction of DNA replication stress by HU activates CHK1 by autophosphorylation. This leads to cell cycle arrest and recruits the DNA repair protein WRN to promote DNA repair and cell survival. In such cells, addition of the CHK1 inhibitor 9a propels DNA damage and apoptosis.
Ramy Ashry, Mohamed Abdelsalam, Julia Hausen, Christoph Hieber, Yanira Zeyn, Anne‐Christin Sarnow, Matthias Schmidt, Sara Najafi, Ina Oehme, Matthias Bros, Jia‐Xuan Chen, Mario Dejung, Wolfgang Sippl, Oliver H. Krämer   +13 more
wiley   +1 more source

Editorial: The role of adjuvant and neoadjuvant therapy in resectable esophageal cancer. [PDF]

Front Oncol
Li X, Cong Z, Qiang Y.
europepmc   +1 more source

A CASE OF ESOPHAGEAL CARCINOSARCOMA WITH RECTAL CANCER

, 1980
Hideto SASAKI, Yoshikatsu Okada, Akifumi Yoshimura, Hisao Tamaki, Hiromichi Goshima, Yoshifumi Kawarada, Ryuji Mizumoto   +6 more
openalex   +2 more sources

Noncoding RNAs in Host–Microbiota Interaction

Animal Research and One Health, EarlyView.
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao, Ni Li, Jingyi Xu, Jianrong Ren, Xiaojun Yang, Xinyi Li, Junhu Yao, Shengru Wu   +7 more
wiley   +1 more source