Results 191 to 200 of about 785,637 (307)

Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally   +7 more
wiley   +1 more source

Objective Swallowing Outcomes After Sparing Contralateral Low‐Neck Elective Radiotherapy in Oropharyngeal Carcinoma: Single‐Institution Clinical Experience

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Dysphagia is a major toxicity of chemoradiation (CRT) for oropharyngeal squamous cell carcinoma (OPSCC). Elective upper‐neck irradiation (UNI), omitting the low neck, may reduce esophageal inlet muscle (EIM) dose and improve swallowing outcomes compared to elective whole‐neck irradiation (WNI).
Rex H. Lee   +7 more
wiley   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

open access: yesPhytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan   +8 more
wiley   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu   +6 more
wiley   +1 more source

Identification of MAPK12 as a Prognostic Biomarker for Esophageal Carcinoma Using Bioinformatics and Machine Learning. [PDF]

open access: yesBiomed Res Int
Gu S   +10 more
europepmc   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

open access: yesPhytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi   +9 more
wiley   +1 more source

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