Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review
Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally +7 more
wiley +1 more source
Aging-associated mechanisms and metabolic vulnerabilities in esophageal carcinoma: an integrative review. [PDF]
Liu Q, Xie Z, Li W, Li M, Qi Y.
europepmc +1 more source
Abstract Objective Dysphagia is a major toxicity of chemoradiation (CRT) for oropharyngeal squamous cell carcinoma (OPSCC). Elective upper‐neck irradiation (UNI), omitting the low neck, may reduce esophageal inlet muscle (EIM) dose and improve swallowing outcomes compared to elective whole‐neck irradiation (WNI).
Rex H. Lee +7 more
wiley +1 more source
Comprehensive Analysis of the Prognostic Significance of ZHX Family Members in Esophageal Carcinoma. [PDF]
You Y +6 more
europepmc +1 more source
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan +8 more
wiley +1 more source
Alleged Misinterpretation of PET-CT in Esophageal Carcinoma Staging: A Medico-Legal Case Report. [PDF]
De Queiroz FR, Jordão NV, Machado DT.
europepmc +1 more source
Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu +6 more
wiley +1 more source
Identification of MAPK12 as a Prognostic Biomarker for Esophageal Carcinoma Using Bioinformatics and Machine Learning. [PDF]
Gu S +10 more
europepmc +1 more source
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
Predictive modeling of flavonoid efficacy against esophageal carcinoma: a comprehensive approach. [PDF]
Pishro P +4 more
europepmc +1 more source

