Results 81 to 90 of about 9,293,248 (412)

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Treatment of Gastrointestinal Sphincters Spasms with Botulinum Toxin A

open access: yesToxins, 2015
Botulinum toxin A inhibits neuromuscular transmission. It has become a drug with many indications. The range of clinical applications has grown to encompass several neurological and non-neurological conditions.
Giuseppe Brisinda   +3 more
doaj   +1 more source

Body Mass Index, Smoking, and Alcohol and Risks of Barrett’s Esophagus and Esophageal Adenocarcinoma: A UK Prospective Cohort Study [PDF]

open access: yes, 2014
BACKGROUND: The timing of the risk factors cigarette smoking, alcohol and obesity in the development of Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) is unclear.
Cheong, Edward   +6 more
core   +1 more source

Multi-layered Free-form 3D Cell-printed Tubular Construct with Decellularized Inner and Outer Esophageal Tissue-derived Bioinks

open access: yesScientific Reports, 2020
The incidences of various esophageal diseases (e.g., congenital esophageal stenosis, tracheoesophageal fistula, esophageal atresia, esophageal cancer) are increasing, but esophageal tissue is difficult to be recovered because of its weak regenerative ...
Hyoryung Nam   +10 more
semanticscholar   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Comprehensive Analysis of N6-Methyladenosine (m6A) RNA Methylation Regulators and Tumour Microenvironment Cell Infiltration Involving Prognosis and Immunotherapy in Gastroesophageal Adenocarcinomas

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2022
Objective. Gastroesophageal adenocarcinoma (GEA) is a high deadly and heterogeneous cancer. RNA N6-methyladenosine (m6A) modification plays a non-negligible role in shaping individual tumour microenvironment (TME) characterizations.
Duanrui Liu   +13 more
doaj   +1 more source

Deep-learning models in medical image analysis: Detection of esophagitis from the Kvasir Dataset [PDF]

open access: yesarXiv, 2023
Early detection of esophagitis is important because this condition can progress to cancer if left untreated. However, the accuracies of different deep learning models in detecting esophagitis have yet to be compared. Thus, this study aimed to compare the accuracies of convolutional neural network models (GoogLeNet, ResNet-50, MobileNet V2, and ...
arxiv  

A fully resolved active musculo-mechanical model for esophageal transport [PDF]

open access: yesJournal of Computational Physics, Volume 298, 1 October 2015, Pages 446-465, 2015
Esophageal transport is a physiological process that mechanically transports an ingested food bolus from the pharynx to the stomach via the esophagus, a multi-layered muscular tube. This process involves interactions between the bolus, the esophagus, and the neurally coordinated activation of the esophageal muscles.
arxiv   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Bilateral Phrenic Nerve Block For the Treatment of Intractable Hiccup in a Palliative Care Patient: A Case Report

open access: yesBezmiâlem Science, 2019
Hiccup is the characteristic voice caused by the sudden closure of the glottis during the contraction of the muscles of respiration especially diaphragm. It usually ends spontaneously in a short time.
Mustafa SÜREN   +5 more
doaj   +1 more source

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