Results 41 to 50 of about 1,110,911 (288)

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni   +4 more
wiley   +1 more source

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

open access: yesHepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres   +21 more
wiley   +1 more source

Sequential Management of Corrosive Esophageal Perforation in a Low-Resource Setting – Case Illustration

open access: yesNigerian Journal of Medicine
Corrosive esophageal injury in children usually occurs following accidental ingestion of corrosives. Suicidal or homicidal injury in children is rare. The degree and extent of injury depend on the nature of corrosives, the volume of corrosive ingested ...
Ikponmwosa Gold   +7 more
doaj   +1 more source

Spontaneous Esophageal Injury: Esophageal Intramural Hematoma

open access: yesJournal of the Chinese Medical Association, 2009
Acute chest pain can indicate a life-threatening condition and it is important for physicians to diagnose and treat it as a matter of urgency. We report 1 rare case of esophageal intramural hematoma (IMH) that presented with chest pain at the emergency department and which was initially clinically suspected to be due to aortic dissection.
Chiu, Yu-Hui   +5 more
openaire   +2 more sources

Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]

open access: yes, 2005
Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Jauch, Karl-Walter   +2 more
core   +1 more source

A Transnasal Endoscope for Robotically Assisted Gastroscopy

open access: yesAdvanced Robotics Research, EarlyView.
This work introduces a 4.25 mm diameter magnetically navigated transnasal endoscope for upper gastrointestinal (GI) screening and intervention. The system enables precise remote steering throughout the upper GI tract and is demonstrated through in vitro and in vivo experiments, including the robotic execution of preprogrammed retroflexions, trans ...
Alexandre Mesot   +6 more
wiley   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

open access: yesHepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr   +19 more
wiley   +1 more source

Evaluation of Different Surgical Techniques to Repair Iatrogenic Esophageal Injury; an Experimental Study [PDF]

open access: yes, 2015
Objective: Esophageal perforation during anterior spine surgery is a rare but serious complication that may lead to death, if not managed properly.
Aytekin, Hikmet   +6 more
core   +3 more sources

Determination of the effects of cryoablation for atrial fibrillation on esophageal functions

open access: yesAnatolian Journal of Cardiology, 2020
Objective: Periesophageal vagal plexus injury is a complication of cryoablation for atrial fibrillation (AF). The aim of this study is to investigate the effect of cryoablation on esophageal functions and to determine the relationship between esophageal ...
Muhammet Buğra Karaaslan   +10 more
doaj   +1 more source

An Activity‐Reinforced P‐Modified Single‐Atom Cu Nanozyme Potentiates IDO Blockade‐Induced Tumor Radiotherapy

open access: yesAdvanced Science, EarlyView.
A phosphorus‐modified single‐atom copper nanozyme delivering the IDO1 inhibitor 1‐methyl‐tryptophan enhances breast cancer radioimmunotherapy by simultaneously relieving hypoxia and inducing immunogenic cell death through dual enzyme activities while blocking tryptophan metabolism to suppress regulatory T cell function.
Wei Zhao   +11 more
wiley   +1 more source

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