Results 61 to 70 of about 1,110,911 (288)

Differentially Expressed mRNAs and Potential Mechanisms of Radiation-Induced TUT4 Esophageal Cell Injury

Dose-Response, 2022
Radiation-induced esophageal injury remains a limitation for the process of radiotherapy for lung and esophageal cancer patients. Esophageal epithelial cells are extremely sensitive to irradiation, nevertheless, factors involved in the radiosensitivity ...
Zhiqiang Sun, Jiaqi Zhang, Fanye Zeng, Shuyu Zhang, Zhifang Chai, Judong Luo, Jianping Cao   +6 more
doaj   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

A unique case of esophageal perforation caused by prickly pears [PDF]

, 2016
This is a report of a previously healthy 20-year-old male presenting with the sensation of a foreign object being stuck in the throat and difficulty speaking after the ingestion of 2 prickly pears.
Borg Xuereb, Hermann K., Malaguti, Stefan   +1 more
core  

Using Esophageal Pressures to Improve Oxygenation and Compliance in Acute Lung Injury

, 2018
The New England Journal of Medicine article, “Using Esophageal Pressures to Improve Oxygenation and Compliance in Acute Lung Injury,” showed that ventilator adjustments guided by using esophageal pressure for estimation of transpulmonary pressure ...
Connie Wang, Edward Bittner
core   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

Finerenone attenuates experimental autoimmune myocarditis and modulates cardiac macrophage and Th17-cell responses

Frontiers in Cardiovascular Medicine
IntroductionAutoimmune myocarditis is characterized by immune-mediated myocardial injury and remodeling. However, whether the selective nonsteroidal mineralocorticoid receptor antagonist finerenone modulates the cardiac cellular microenvironment in ...
Pengchong Du, Pengchong Du, Pengchong Du, Pengchong Du, Yameng Zhao, Yameng Zhao, Yameng Zhao, Yameng Zhao, Rilige Su, Rilige Su, Rilige Su, Rilige Su, Ke Hu, Ke Hu, Ke Hu, Ke Hu, Lingyu Bai, Lingyu Bai, Lingyu Bai, Lingyu Bai, Xinyue Cui, Xinyue Cui, Xinyue Cui, Xinyue Cui, Zhaowei Sun, Zhaowei Sun, Zhaowei Sun, Zhaowei Sun, Yu Yang, Yu Yang, Yu Yang, Yu Yang, Xieze Wei, Bolin Jiao, Bolin Jiao, Bolin Jiao, Bolin Jiao, Siyu Guan, Siyu Guan, Siyu Guan, Siyu Guan, Deheng Han, Deheng Han, Deheng Han, Deheng Han, Yang Lu, Yang Lu, Yang Lu, Yang Lu, Jinying Zhang, Jinying Zhang, Jinying Zhang, Jinying Zhang, Junnan Tang, Junnan Tang, Junnan Tang, Junnan Tang   +56 more
doaj   +1 more source

Esophageal Reconstruction for Esophageal Stricture after Corrosive Injury.

Nippon Jibiinkoka Gakkai Kaiho, 1999
Swallowing a corrosive agent (alkali or acid) often causes severe pharyngeal, laryngeal or esophageal stricture (caustic stenosis), which is usually very difficult to treat. This paper reports two cases of esophageal stricture treated by esophagoplasty. Both cases had attempted suicide by swallowing a sodium hydroxide solution or acid.
Hatta, Chihiro, Ogasawara, Hiroshi, Tsuyu, Masakazu, Kakibuchi, Masao, Yamada, Nobuyuki, Nakai, Yoshiyuki, Yoshinaga, Kazumasa, Sakagami, Masafumi   +7 more
openaire   +3 more sources

Impact of esophageal temperature monitoring guided atrial fibrillation ablation on preventing asymptomatic excessive transmural injury

Journal of Arrhythmia, 2016
Background: Even with the use of a reduced energy setting (20–25 W), excessive transmural injury (ETI) following catheter ablation of atrial fibrillation (AF) is reported to develop in 10% of patients.
Kunihiko Kiuchi, MD, FHRS, Katsunori Okajima, MD, Akira Shimane, MD, Gaku Kanda, MD, Kiminobu Yokoi, MD, Jin Teranishi, MD, Kousuke Aoki, MD, Misato Chimura, MD, Takayoshi Toba, MD, Shogo Oishi, MD, Takahiro Sawada, MD, Yasue Tsukishiro, MD, Tetsuari Onishi, MD, Seiichi Kobayashi, MD, Yasuyo Taniguchi, MD, Shinichiro Yamada, MD, Yoshinori Yasaka, MD, Hiroya Kawai, MD, Akihiro Yoshida, MD, Koji Fukuzawa, MD, Mitsuaki Itoh, MD, Kimitake Imamura, MD, Ryudo Fujiwara, MD, Atsushi Suzuki, MD, Tomoyuki Nakanishi, MD, Soichiro Yamashita, MD, Ken-ichi Hirata, MD, Hiroshi Tada, MD, FHRS, Hiro Yamasaki, MD, Yoshihisa Naruse, MD, Miyako Igarashi, MD, Kazutaka Aonuma, MD   +31 more
doaj   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source